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Interval estimations for parameters of gompertz model with time-dependent covariate and right censored data

机译:带有时间相关协变量和右删失数据的Gompertz模型参数的区间估计

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摘要

There are numerous parametric models for analyzing survival data such as exponential, Weibull, log-normal and gamma.udOne of such models is the Gompertz model which is widely used in biology and demography. Most of these models areudextended to new forms for accommodating different types of censoring mechanisms and different types of covariates. Inudthis paper the performance of the Gompertz model with time-dependent covariate in the presence of right censored dataudwas studied. Moreover, the performance of the model was compared at different censoring proportions (CP) and sampleudsizes. Also, the model was compared with fixed covariate model. In addition, the effect of fitting a fixed covariate modeludwrongly to a data with time-dependent covariate was studied. Finally, two confidence interval estimation techniques,udWald and jackknife, were applied to the parameters of this model and the performance of the methods was compared.
机译:有许多用于分析生存数据的参数模型,例如指数,威布尔(Weibull),对数正态和伽玛(γ)。此类模型之一是Gompertz模型,该模型广泛用于生物学和人口统计学。这些模型中的大多数被扩展为新形式,以适应不同类型的审查机制和不同类型的协变量。本文研究了在存在右删失数据的情况下具有时间相关协变量的Gompertz模型的性能。此外,在不同的审查比例(CP)和样本 udsizes下,比较了模型的性能。此外,将模型与固定协变量模型进行了比较。此外,还研究了将固定协变量模型错误地拟合到具有时间依赖性协变量的数据的效果。最后,将两种置信区间估计技术 udWald和jackknife应用于该模型的参数,并对方法的性能进行了比较。

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