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Rapid and accurate detection of KRAS mutations in colorectal cancers using the isothermal-based optical sensor for companion diagnostics

机译：使用基于等温的光学传感器进行伴随诊断的基于等温的光学传感器快速准确地检测结肠直肠癌中的KRAS突变

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Choong Eun Jin; Seung-Seop Yeom; Bonhan Koo; Tae Yoon Lee; Jeong Hoon Lee; Yong Shin; Seok-Byung Lim;
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1. Validation of companion diagnostic for detection of mutations in Codons 12 and 13 of the KRAS gene in patients with metastatic colorectal Cancer: Analysis of the NCIC CTG CO.17 trial [J] . HarbisonC.T., HorakC.E., LedeineJ.-M., Archives of pathology & laboratory medicine . 2013,第6期

机译：转移性结直肠癌患者KRAS基因密码子12和13突变检测的伴随诊断方法的验证：NCIC CTG CO.17试验的分析
2. Companion-diagnostic testing limited to KRAS codons 12 and 13 misses 17% of potentially relevant RAS mutations in colorectal cancer [J] . NetzelB.C., GrebeS.K.G. Clinica chimica acta: International journal of clinical chemistry and applied molecular biology . 2013,第Null期

机译：仅限KRAS密码子12和13的伴随诊断测试遗漏了大肠癌中潜在相关RAS突变的17％
3. Detection of Emphasis Type="Italic"KRAS/Emphasis Mutations in Plasma DNA Using a fully Automated Rapid Detection System in Colorectal Cancer Patients [J] . Kazuhisa Hosoya, Satoshi Matsusaka, Tomomi Kashiwada, Pathology oncology research: POR . 2017,第4期

机译：使用全自动快速检测系统检测大肠癌患者血浆DNA中 KRAS 突变
4. Isolation of Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer Using Label-Free Microfluidic Technology for Enumeration and Detection of KRAS, BRAF, PIK3CA Mutation [C] . Haiyan Emily Liu, Evelyn Kidess-Sigal, Melanie Triboulet, International Molecular Medicine Tri-Conference. . 2016

机译：使用无标记微流体技术分离转移性结肠直肠癌患者的循环肿瘤细胞进行募准和检测KRA，BRAF，PIK3CA突变
5. Glucose deprivation selects for KRAS and BRAF mutations in colorectal cancer. [D] . Yun, Jihye. 2009

机译：葡萄糖剥夺选择结直肠癌中的KRAS和BRAF突变。
6. Rapid and accurate detection of KRAS mutations in colorectal cancers using the isothermal-based optical sensor for companion diagnostics [O] . Choong Eun Jin, Seung-Seop Yeom, Bonhan Koo, 2017

机译：使用基于等温的光学传感器快速准确地检测大肠癌中的KRAS突变以进行伴随诊断
7. PRM93 Validation of A Global Economic Model to Evaluate The Cost-Effectiveness Of Targeted Treatments Using Companion Diagnostics In Advanced/Metastatic Cancer Treatment Using Kras Testing For Cetuximab Therapy In Metastatic Colorectal Cancer [O] . Mathurin K., Beauchemin C., Lachaine J. 2014

机译：PRM93验证了一种全球经济模型，以评估针对性疗法的成本-效果，该疗法在伴随/诊断转移性结直肠癌中使用克拉斯检验的西妥昔单抗疗法用于晚期/转移性癌症治疗中的伴随诊断

Rapid and accurate detection of KRAS mutations in colorectal cancers using the isothermal-based optical sensor for companion diagnostics

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