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Naphthyl and Coumarinyl Biarylpiperazine Derivatives as Highly Potent Human b-Secretase Inhibitors. Design, Synthesis, and Enzymatic BACE-1 and Cell Assays

机译：萘基和香豆素丙基哌嗪衍生物作为高效的人B-分泌酶抑制剂。设计，合成和酶促BACE-1和细胞测定

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1. Naphthyl and coumarinyl biarylpiperazine derivatives as highly potent human beta-secretase inhibitors. Design, synthesis, and enzymatic BACE-1 and cell assays [J] . Garino C, Tomita T, Pietrancosta N, Journal of Medicinal Chemistry . 2006,第14期

机译：萘基和香豆基联芳基哌嗪衍生物作为高效的人β分泌酶抑制剂。设计，合成和酶促BACE-1和细胞测定
2. 1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor Xa inhibitors. Part 3: Design, synthesis and SAR of orally bioavailable benzamidine-P4 inhibitors. [J] . Jia ZJ, Wu Y, Huang W, Bioorganic and Medicinal Chemistry Letters . 2004,第5期

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4. Induction of G2/M phase arrest and apoptosis by potent antitumor thirty-two-8-oxo-8H-acenaphtho1,2-bpyrrole-9-carbonitrile derivative in human cervix carcinoma cells [C] . rn, rn, rn Asian Pacific Confederation of Chemical Engineering congress . 2008

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6. Design synthesis molecular modelling and biological evaluation of novel3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenaseinhibitors [O] . Sahar A. Ali, Samir Mohamed Awad, Ahmed Mohammed Said, 2020

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7. Structure-Based Design of Potent and Selective Cell-Permeable Inhibitors of Human b-Secretase (BACE-1) [O] . -1

机译：基于结构的有效和选择性细胞可渗透抑制剂的人B-分泌酶（BACE-1）的设计

Naphthyl and Coumarinyl Biarylpiperazine Derivatives as Highly Potent Human b-Secretase Inhibitors. Design, Synthesis, and Enzymatic BACE-1 and Cell Assays

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