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PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events

机译：PI3K信号通路通过Pik3Ca mRNA过表达和前列腺肿瘤复制增益激活，但Pik3Ca，BRAF，KRAS和AKT1突变是不常见的事件

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Laia Agell; Silvia Hernández; Marta Salido; Silvia de Muga; Nuria Juanpere; Montserrat Arumí-Uria; Silvia Menendez; Marta Lorenzo; José A Lorente; Sergio Serrano; Josep Lloreta;
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1. PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events [J] . Laia Agell, Silvia Hernández, Marta Salido, Modern Pathology . 2011,第3期

机译：PI3K信号通路被前列腺肿瘤中的PIK3CA mRNA过表达和复制增加激活，但PIK3CA，BRAF，KRAS和AKT1突变很少发生
2. 803 PI3K signalling pathway is activated by PIK3CA gain and overexpression in prostate tumours, but PI3KCA, BRAF, KRAS AND AKT1 mutations are an infrequent event [J] . L.Agell, S.Hernandez, S.de Muga, European Journal of Cancer Supplements . 2010,第5期

机译：803 PI3K信号通路被前列腺肿瘤中的PIK3CA增益和过表达激活，但PI3KCA，BRAF，KRAS和AKT1突变很少发生
3. Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations. [J] . Hafner C, Landthaler M, Vogt T Experimental dermatology . 2010,第8期

机译：非黑色素瘤皮肤癌中PI3K / AKT信号通路的激活不由致癌性PIK3CA和AKT1热点突变介导。
4. Isolation of Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer Using Label-Free Microfluidic Technology for Enumeration and Detection of KRAS, BRAF, PIK3CA Mutation [C] . Haiyan Emily Liu, Evelyn Kidess-Sigal, Melanie Triboulet, International Molecular Medicine Tri-Conference. . 2016

机译：使用无标记微流体技术分离转移性结肠直肠癌患者的循环肿瘤细胞进行募准和检测KRA，BRAF，PIK3CA突变
5. The role of mutational activation of RAS and PI3K signaling pathways in human tumors: Biologic and therapeutic implications. [D] . Halilovic, Ensar. 2009

机译：RAS和PI3K信号通路突变激活在人类肿瘤中的作用：生物学和治疗意义。
6. BRAF KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis? [O] . Sérgia Velho, Cátia Moutinho, Luís Cirnes, 2008

机译：大肠锯齿状息肉和癌症中的BRAFKRAS和PIK3CA突变：大肠癌变的主要或次要遗传事件？
7. Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations [O] . Christian Hafner, Michael Landthaler, Thomas Vogt 2010

机译：在非黑色素瘤皮肤癌中的PI3K / AKT信号传导途径的激活未被致癌PIK3CA和AKT1热点突变介导

PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events

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