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In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi)

机译：新型异羟肟酸和苯甲酰胺型组蛋白脱乙酰酶抑制剂（HDACI）的体外评估

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Annabelle Friedrich; Ann-Sophie Assmann; Lena Schumacher; Jana v. Stuijvenberg; Matthias U. Kassack; Wolfgang A. Schulz; Wynand P. Roos; Finn K. Hansen; Marc Pflieger; Thomas Kurz; Gerhard Fritz;
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1. Histone Deacetylase Inhibitor (HDACi) Suberoylanilide Hydroxamic Acid (SAHA)-mediated Correction of α1-Antitrypsin Deficiency [J] . Marion Bouchecareilh, Darren Hutt, Patricia Szajner, The Journal of biological chemistry . 2012,第45期

机译：组蛋白脱乙酰酶抑制剂（HDACI）Suberoylanilide羟肟酸（SAHA）介导的α1-抗胰蛋白酶缺乏的校正
2. Antitumor effects of histone deacetylase inhibitor suberoylanilide hydroxamic acid in epidermal growth factor receptor-mutant non-small-cell lung cancer lines in vitro and in vivo [J] . Wei Ye, Zhou Fangzheng, Lin Zhenyu, Anti-cancer drugs . 2018,第3期

机译：组蛋白脱乙酰酶抑制剂苯甲酰苯酚羟肟酸异化物体在体外和体内体内抗甲酰酶抑制剂羟基苯酚的抗肿瘤作用
3. Development of Purine-Based Hydroxamic Acid Derivatives: Potent Histone Deacetylase Inhibitors with Marked in Vitro and in Vivo Antitumor Activities [J] . Chen Yong, Wang Xiaoyan, Xiang Wei, Journal of Medicinal Chemistry . 2016,第11期

机译：嘌呤为基础的异羟肟酸衍生物的开发：具有强大的体外和体内抗肿瘤活性的组蛋白脱乙酰基酶抑制剂。
4. Construction of a novel scoring function by using a genetic algorithm for virtual screening of histone deacetylase inhibitors (HDACi) [C] . Xiang Yuhong, Wei Yanbo, Zhang Zhuoyong, International Conference on Natural Computation . 2013

机译：通过使用遗传算法对组蛋白脱乙酰基酶抑制剂（HDACi）进行虚拟筛选的新型评分功能的构建
5. The structural requirements of histone deacetylase (HDAC) inhibitors: Suberoylanilide hydroxamic acid (SAHA) analogues modified at C3, C6, and C7 positions enhance selectivity [D] . Choi, Sun Ea 2012

机译：组蛋白脱乙酰基酶（HDAC）抑制剂的结构要求：在C3，C6和C7位置修饰的Suberoylanilide异羟肟酸（SAHA）类似物可提高选择性
6. In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi) [O] . Annabelle Friedrich, Ann-Sophie Assmann, Lena Schumacher, 2020

机译：新型异羟肟酸和苯甲酰胺型组蛋白脱乙酰基酶抑制剂（HDACi）的遗传毒性危害的体外评估
7. Enhanced In Vitro Expression Of NKG2D Ligands MIC A And MIC B With Histone Deacetylase Inhibitor (HDACi) Romidepsin In Pediatric Leukemia And Lymphomas: Potential for Natural Killer Cell Mediated Targeted Adoptive Cellular Immunotherapy (ACI) [O] . Satwani P., Saha A., Bavishi S., 2009

机译：组蛋白去乙酰化酶抑制剂（HDACi）罗米地辛在儿童白血病和淋巴瘤中增强了NKG2D配体MIC A和MIC B的体外表达：天然杀伤细胞介导的靶向过继细胞免疫治疗（ACI）的潜力

In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi)

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