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FLT3 Internal Tandem Duplication in Patients With Acute Myeloid Leukemia Is Readily Detectable in a Single Next-Generation Sequencing Assay Using the Pindel Algorithm

机译：FLT3内部串联复制患者急性髓性白血病患者使用Pindel算法在单一的下一代测序测定中易于检测

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Borahm Kim; SooJeong Kim; Seung-Tae Lee; Yoo Hong Min; Jong Rak Choi;
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1. Correction to: Hybridization capture-based next-generation sequencing reliably detects FLT3 mutations and classifies FLT3 -internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis [J] . Rong He, Daniel J. Devine, Zheng Jin Tu, Modern Pathology . 2020 ,第3期

机译：校正至：基于杂交的捕获的下一代测序可靠地检测FLT3突变，并在急性髓性白血病中分类FLT3-间串联复制等位基因：标准片段分析的比较研究
2. Hybridization capture-based next generation sequencing reliably detects FLT3 mutations and classifies FLT3 -internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis [J] . Rong He, Daniel J. Devine, Zheng Jin Tu, Modern Pathology . 2020 ,第3期

机译：基于杂交的基于捕获的下一代测序可靠地检测FLT3突变，并在急性髓性白血病中分类FLT3 - Internal串联复制等位基因：标准片段分析的比较研究
3. Efficacy and Safety of Single-Agent Quizartinib, a Potent and Selective FLT3 Inhibitor (FLT3i), in Patients (pts) With FLT3-Internal Tandem Duplication (FLT3-ITD) - Mutated Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) Enrolled in the Global, Phase 3, Randomized Controlled QuANTUM-R Trial [J] . Jonas Brian A., Cortes Jorge E., Khaled Samer K., Clinical lymphoma, myeloma & leukemia . 2019 ,第Suppla1期

机译：单药剂Quizartinib，一种有效和选择性FLT3抑制剂（FLT3i），患者（PTS）的疗效和安全性，具有FLT3 - 内部串联复制（FLT3-ITD） - 突变复发/难治（R / R）急性髓性白血病（AML ）注册全球，第3阶段，随机控制量子-R试验
4. Tandem mass spectrometry characterizes the related substances of second generation FLT3 inhibitor Quizartinib, anti cancer compound for myeloid leukemia [C] . Saravanan Subramaniyan, Arvind Thyagarajan, Rampriya Uthayakumar, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：串联质谱表征第二代FLT3抑制剂Quizartinib的相关物质，用于髓性白血病的抗癌化合物
5. Partial tandem duplication of the ALL1 gene in acute myeloid leukemia. [D] . Strout, Matthew Perry. 1997

机译：ALL1基因在急性髓细胞性白血病中的部分串联重复。
6. FLT3 Internal Tandem Duplication in Patients With Acute Myeloid Leukemia Is Readily Detectable in a Single Next-Generation Sequencing Assay Using the Pindel Algorithm [O] . Borahm Kim, SooJeong Kim, Seung-Tae Lee, 2019

机译：使用Pindel算法在单个下一代测序分析中即可检测到急性髓性白血病患者的FLT3内部串联重复
7. FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia. [O] . Mead AJ, Linch DC, Hills RK, 2007

机译：与急性髓样白血病患者的FLT3内部串联重复相比，FLT3酪氨酸激酶结构域突变在生物学上有所区别，并且预后要好得多。

FLT3 Internal Tandem Duplication in Patients With Acute Myeloid Leukemia Is Readily Detectable in a Single Next-Generation Sequencing Assay Using the Pindel Algorithm

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