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Synthesis and Biological Evaluation of N2-Substituted 2,4-Diamino-6-cyclohexylmethoxy-5-nitrosopyrimidines and Related 5-Cyano-NNO-azoxy Derivatives as Cyclin-Dependent Kinase 2 (CDK2) Inhibitors

机译：N2取代的2,4-二氨基-6-环己基甲氧基 - 5-亚硝基嘧啶和相关5-氰基 - NNO-偶氮衍生物的合成及生物学评价为细胞周期蛋白依赖性激酶2（CDK2）抑制剂

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Daniela Cortese; Konstantin Chegaev; Stefano Guglielmo; Lan Z. Wang; Bernard T. Golding; Céline Cano; Roberta Fruttero;
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1. Synthesis and Biological Evaluation of N-2-Substituted 2,4-Diamino-6-cyclohexylmethoxy-5-nitrosopyrimidines and Related 5-Cyano-NNO-azoxy Derivatives as Cyclin-Dependent Kinase2 (CDK2) Inhibitors [J] . Cortese Daniela, Chegaev Konstantin, Guglielmo Stefano, ChemMedChem . 2016,第16期

机译：N-2-取代的2,4-二氨基-6-环己基甲氧基-5-亚硝基嘧啶及相关的5-氰基-NNO-氮氧基衍生物作为细胞周期蛋白依赖性激酶2（CDK2）抑制剂的合成及生物学评价
2. Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 30 (GSK-3P) phosphorylation inhibitors [J] . Ping Zhao, Yanzhong Li, Guangwei Gao, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2014,第Null期

机译：N-烷基或芳基取代的异靛蓝衍生物作为潜在的双重细胞周期蛋白依赖性激酶2（CDK2）/糖原合酶激酶30（GSK-3P）磷酸化抑制剂的设计，合成和生物学评估
3. Design, synthesis and biological evaluation of novel histone deacetylase1/2 (HDAC1/2) and cyclin-dependent Kinase2 (CDK2) dual inhibitors against malignant cancer [J] . European Journal of Medicinal Chemistry: Chimie Therapeutique . 2020,第期

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4. Indentification of Pharmacophore Model, Synthesis and biological evaluation of N-phenyl-1-arylamide and N-phenylbenzenesulfonamide derivatives as BACE 1 inhibitors [C] . Wenhai Huang, Haiping Yu, Rong Sheng, 第四届国际分子模拟与信息技术应用学术会议（The 4th International Conference of Molecular Simulations and Applied Informatics Technologies）论文集 . 2008

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7. N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2 [O] . -1

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Synthesis and Biological Evaluation of N2-Substituted 2,4-Diamino-6-cyclohexylmethoxy-5-nitrosopyrimidines and Related 5-Cyano-NNO-azoxy Derivatives as Cyclin-Dependent Kinase 2 (CDK2) Inhibitors

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