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A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells

机译：Trastuzumab和17-AAG的组合诱导ErbB2过表达乳腺癌细胞中增强的泛素蛋白化和溶酶体途径依赖性的ERBB2降解和细胞毒性

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Srikumar M. Raja; Robert J. Clubb; Mitra Bhattacharyya; Manjari Dimri; Hao Cheng; Wei Pan; Cesar Ortega-Cava; Alagarsamy Lakku-Reddi; Mayumi Naramura; Vimla Band; Hamid Band;
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1. A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells. [J] . Raja SM, Clubb RJ, Bhattacharyya M, Cancer biology & therapy . 2008,第10期

机译：曲妥珠单抗和17-AAG的组合在过表达ErbB2的乳腺癌细胞中诱导增强的泛素化和溶酶体途径依赖性ErbB2降解以及细胞毒性。
2. HDAC inhibitor SNDX-275 enhances efficacy of trastuzumab in erbB2-overexpressing breast cancer cells and exhibits potential to overcome trastuzumab resistance. [J] . Huang X, Wang S, Lee CK, Cancer letters . 2011,第1期

机译：HDAC抑制剂SNDX-275可增强曲妥珠单抗在erbB2过表达的乳腺癌细胞中的功效，并具有克服曲妥珠单抗的潜力。
3. Combining lapatinib (GW572016), a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases, with therapeutic anti-ErbB2 antibodies enhances apoptosis of ErbB2-overexpressing breast cancer cells [J] . Wenle Xia, Catherine M Gerard, Leihua Liu, Oncogene . 2005,第41期

机译：拉帕替尼（GW572016）（一种ErbB1和ErbB2酪氨酸激酶的小分子抑制剂）与治疗性抗ErbB2抗体的结合可增强过表达ErbB2的乳腺癌细胞的凋亡
4. Therapeutic Combination of Gold Nanoparticles and LPS as Cytotoxic and Apoptosis Inducer in Breast Cancer Cells [C] . Ali M. Sameen, Majid S. Jabir, Mohammed Q. Al-ani International Conference on Materials Engineering and Science . 2020

机译：金纳米粒子和LPS作为细胞毒性和凋亡诱导剂在乳腺癌细胞中的治疗组合
5. Enhancement of Gemcitabine and Paclitaxel Uptake and Retention in Metastatic Cancer Cells: A Novel Targeted Combination Delivery Approach to Eliminate Breast Cancer in Blood and Lymph [D] . Yu, Jesse. 2020

机译：吉西他滨和紫杉醇吸收的增强和转移性癌细胞的保留：一种小型靶向组合递送方法，消除血液和淋巴中的乳腺癌
6. A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathwaydependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells [O] . Srikumar M. Raja, Robert J. Clubb, Mitra Bhattacharyya, -1

机译：曲妥珠单抗和17-AAG的组合诱导过表达ErbB2的乳腺癌细胞中泛素化增强和溶酶体途径依赖性ErbB2降解以及细胞毒性
7. Trastuzumab in combination with AT-101 induces cytotoxicity and apoptosis in Her2 positive breast cancer cells [O] . Gulcan Bulut, Harika Atmaca, Burcak Karaca 2020

机译：Trastuzumab与AT-101组合诱导细胞毒性和凋亡在HER2阳性乳腺癌细胞中

A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells

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