首页> 外文OA文献 >542. Transduction of Murine, Nonhuman Primate, and Human Hematopoietic Stem Cells (HSCs) by Recombinant AAV Serotype Vectors: Identification of AAV6 as the Most Efficient Serotype for Human HSCs, and Further Augmentation in Transduction Efficiency In Vitro and In Vivo with Point-Mutations of Tyrosine Residues in the Viral Capsid

【2h】

542. Transduction of Murine, Nonhuman Primate, and Human Hematopoietic Stem Cells (HSCs) by Recombinant AAV Serotype Vectors: Identification of AAV6 as the Most Efficient Serotype for Human HSCs, and Further Augmentation in Transduction Efficiency In Vitro and In Vivo with Point-Mutations of Tyrosine Residues in the Viral Capsid

机译：542.通过重组AAV血清型载体进行鼠，非人类灵长类动物和人造造血干细胞（HSC）的转导：AAV6作为人HSC的最有效的血清型，进一步在体外转导效率和体内突变的进一步增加病毒衣壳中的酪氨酸残基

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

著录项
引文网络
相似文献
相关主题

著录项

作者

展开▼
作者单位

展开▼
年度 2013
总页数
原文格式 PDF
正文语种
中图分类

相似文献

外文文献
中文文献
专利

1. Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo [J] . LIUJIANG SONG, M. ARIEL KAUSS, ETANA KOPIN, Cytotherapy . 2013,第8期

机译：在体外和体内异种移植小鼠模型中优化衣壳修饰的AAV6血清型载体在人造血干细胞中的转导效率
2. Comparison of the ability of adeno-associated viral vectors pseudotyped with serotype 2, 5, and 8 capsid proteins to mediate efficient transduction of the liver in murine and nonhuman primate models. [J] . Davidoff AM, Gray JT, Ng CY, Molecular therapy: the journal of the American Society of Gene Therapy . 2005,第6期

机译：比较血清型2、5和8衣壳蛋白假型化的腺相关病毒载体介导鼠和非人灵长类动物模型中肝脏的有效转导的能力。
3. Molecular analysis of vector genome structures after liver transduction by conventional and self-complementary adeno-associated viral serotype vectors in murine and nonhuman primate models. [J] . Sun X, Lu Y, Bish LT, Human gene therapy . 2010,第6期

机译：常规和自互补腺相关病毒血清型载体在鼠和非人灵长类动物模型中进行肝转导后，载体基因组结构的分子分析。
4. High-Efficiency Transduction of Primary Human Hematopoietic Stem Cells and Erythroid Lineage-Restricted Expression by Optimized AAV6 Serotype Vectors In Vitro and in a Murine Xenograft Model In Vivo [O] . Liujiang Song, Xiaomiao Li, Giridhara R. Jayandharan, -1

机译：原代人造血的高效率转导通过干优化aaV6血清型载体在体外和在小鼠异种移植模型的体内细胞和红细胞谱系限制性表达
5. Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo [O] . Experimental Hematology Laboratory, Department of Physiology, School of Basic Medical Sciences, Central South University, Changsha, China ( host institution ), Song, Liujiang ( UF author ), Kauss, M. Ariel ( author ), 2013

机译：在体外和体内异种移植小鼠模型中优化衣壳修饰的AAV6血清型载体在人原代造血干细胞中的转导效率

著录项

引文网络

相似文献

相关主题

期刊订阅