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Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers

机译：具有抗癌剂AMPI-109的基因组功能遗传筛网将PRL-3鉴定为三阴性乳腺癌中的致癌钳

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Hamid H. Gari; Christy M. Gearheart; Susan Fosmire; Gregory D. DeGala; Zeying Fan; Kathleen C. Torkko; Susan M. Edgerton; M. Scott Lucia; Rahul Ray; Ann D. Thor; Christopher C. Porter; James R. Lambert;
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1. 三阴性乳腺癌患者因新辅助或辅助化疗引起的早发性心脏事件与其基因组DNA中某些新的自噬相关单核苷酸多态性的相关性研究:一项真实世界研究 [J] . Binliang Liu, Yuhui Zhang, Binghe Xu, 癌症（英文版） . 2019,第007期
2. Loss of the oncogenic phosphatase PRL-3 promotes a TNF-R1 feedback loop that mediates triple-negative breast cancer growth [J] . H H Gari, G D DeGala, M S Lucia, Oncogenesis. . 2016,第8期

机译：致癌磷酸酶PRL-3的缺失促进了TNF-R1反馈回路，该回路介导三阴性乳腺癌的生长
3. Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss [J] . Liu Xijuan, Simon Jeremy M., Xie Haibiao, Molecular cell . 2020,第6期

机译：基因组围绕筛选将SFMBT1识别为癌症中的致癌驱动器，VHL损失
4. Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer [J] . Hui Liu, Charles J. Murphy, Florian A. Karreth, Cancer discovery. . 2018,第3期

机译：三重阴性乳腺癌小鼠模型中鉴定和靶向散发性致癌畸变
5. Direct Detection of Metabolic Changes in Genetically Modified Triple-Negative Breast Cancer Cells by Laser Ablation Electrospray Ionization Mass Spectrometry [C] . Hang Li, Hehua Huang, Bindesh Shrestha, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：通过激光烧蚀电喷雾电离质谱法直接检测遗传改性三重阴性乳腺癌细胞的代谢变化
6. Preclinical exploration of novel small molecules as anticancer agents in triple-negative and HER2/neu-positive breast cancers. [D] . Weng, Shu-Chuan. 2008

机译：在三阴性和HER2 / neu阳性乳腺癌中作为抗癌药的新型小分子的临床前探索。
7. Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers [O] . Hamid H. Gari, Christy M. Gearheart, Susan Fosmire, 2016

机译：使用抗癌剂AMPI-109进行全基因组功能遗传筛查可确定PRL-3是三阴性乳腺癌的致癌驱动因素
8. 3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer [O] . Barrie Peck, Philip Bland, Ioanna Mavrommati, 2021

机译：3D功能基因组学屏幕将CREBBP识别为激进的三阴性乳腺癌中的可有理司机

Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers

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