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Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents

机译：JNK的抑制使缺氧结肠癌细胞敏化至DNA损伤剂

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Irina A. Vasilevskaya; Muthu Selvakumaran; Lucia Cabal Hierro; Sara R. Goldstein; Jeffrey D. Winkler; Peter J. ODwyer;
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1. Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents [J] . Vasilevskaya Irina A., Selvakumaran Muthu, Hierro Lucia Cabal, Clinical cancer research: an official journal of the American Association for Cancer Research . 2015,第18期

机译：JNK的抑制使缺氧的结肠癌细胞对DNA损伤剂敏感。
2. Abrogation of the G2 checkpoint by inhibition of Wee-1 kinase results in sensitization of p53-deficient tumor cells to DNA-damaging agents. [J] . Leijen S, Beijnen JH, Schellens JH Current clinical pharmacology . 2010,第3期

机译：通过抑制Wee-1激酶来废除G2检查点会导致p53缺陷的肿瘤细胞对DNA损伤剂敏感。
3. Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents. [J] . Hirai H, Iwasawa Y, Okada M, Molecular cancer therapeutics . 2009,第11期

机译：MK-1775对Wee1激酶的小分子抑制选择性地使p53缺陷的肿瘤细胞对DNA损伤剂敏感。
4. Effect of Inhibition of DLC-1 Gene Expression by RNA Interference (RNAi) on Cell Proliferation and Migration in Colon Cancer LoVo Cell Line [C] . Peiling Huang, Yueling Jin, Xiaoqiang Tian, International Forum on Progress on Post-Genome Technologies(5'IFPT); 20070910-11; Suzhou(CN) . 2007

机译：RNA干扰（RNAi）抑制DLC-1基因表达对结肠癌LoVo细胞株细胞增殖和迁移的影响
5. Overexpression of nuclear and mitochondrial-targeted MPG sensitizes breast cancer cells to chemotherapeutic agents and results in an imbalance in DNA repair [D] . Limp-Foster, Melissa M. 2001

机译：核和线粒体靶向的MPG的过表达使乳腺癌细胞对化疗药物敏感并导致DNA修复失衡
6. Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNADamaging Agents [O] . Irina A. Vasilevskaya, Muthu Selvakumaran, Lucia Cabal Hierro, -1

机译：JNK的抑制使缺氧的结肠癌细胞对DNA敏感。破坏剂
7. MET Inhibition Results in DNA Breaks and Synergistically Sensitizes Tumor Cells to DNA-Damaging Agents Potentially by Breaching a Damage-Induced Checkpoint Arrest [O] . Medová, Michaela, Aebersold, Daniel Matthias, Blank-Liss, Wieslawa, 2010

机译：MET抑制导致DNA断裂，并可能通过突破损伤诱导的检查点逮捕而协同地使肿瘤细胞对DNA损伤剂敏感。
8. Experimental Investigations on the Relationship Between Radiation Dose and Sensitization of Hypoxic Cells by Electron Affinic Compounds. Coordinated Programme on Improvement in Radiotherapy of Cancer Using Modifiers of Radiosensit [R] . Revesz, L. 1981

机译：电子亲和化合物对辐射剂量与低氧细胞敏感性关系的实验研究。利用放射治疗改良剂改善癌症放射治疗的协调计划

Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents

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