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Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment

机译：基于结构的pH依赖性抗体结合，用于固体肿瘤微环境的选择性靶向

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Traian Sulea; Nazanin Rohani; Jason Baardsnes; Christopher R. Corbeil; Christophe Deprez; Yuneivy Cepero-Donates; Alma Robert; Joseph D. Schrag; Marie Parat; Mélanie Duchesne; Maria L. Jaramillo; Enrico O. Purisima; John C. Zwaagstra;
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1. Current strategies in antibody engineering: Fc engineering and pH-dependent antigen binding, bispecific antibodies and antibody drug conjugates [J] . Karen J. Vincent, Mauro Zurini Biotechnology Journal: Healthcare,Nutrition,Technology . 2012,第12期

机译：抗体工程的当前策略：Fc工程和pH依赖性抗原结合，双特异性抗体和抗体药物偶联物
2. Visualization of the membrane engineering concept: Evidence for the specific orientation of electroinserted antibodies and selective binding of target analytes [J] . KoklaA., BlouchosP., LivaniouE., Journal of molecular recognition: JMR . 2013,第12期

机译：膜工程概念的可视化：电插入抗体的特定方向和目标分析物选择性结合的证据
3. Inhibitory Fc gamma RIIb-Mediated Soluble Antigen Clearance from Plasma by a pH-Dependent Antigen-Binding Antibody and Its Enhancement by Fc Engineering [J] . Iwayanagi Yuki, Igawa Tomoyuki, Maeda Atsuhiko, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2015,第7期

机译：pH依赖性抗原结合抗体抑制血浆中的FcγRIIb介导的可溶性抗原清除及其通过Fc工程增强
4. Structure-Guided Engineering of Broadly Neutralizing Antibodies Targeting the CD4 Binding Site of HIV-1 Envelope [C] . Yen-Ting Lai, Qingbo Liu, Peng Zhang, Protein Engineering Summit. . 2018

机译：靶向靶向HIV-1包络CD4结合位点的宽度中和抗体的结构引导工程
5. Synthetic antibody engineering: i) Targeting glycans; ii) Features of D5 variants that are required for high affinity binding to HIV-1 5-Helix [D] . Stewart, Alex Aaron 2013

机译：合成抗体工程：i）靶向聚糖； ii）高亲和力与HIV-1 5-螺旋结合所需的D5变体的特征
6. Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment [O] . Traian Sulea, Nazanin Rohani, Jason Baardsnes, 2020

机译：pH依赖性抗体结合的基于结构的工程学可选择性靶向固体肿瘤微环境
7. Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGFβ1 antibody [O] . Dana M. Lord, Julie J. Bird, Denise M. Honey, 2018

机译：基于结构的工程，恢复同种型选择性抗TGFβ1抗体的高亲和力结合
8. Novel approaches to cancer targeting using epitope-binding properties that mimic monoclonal antibodies [R] . 1998

机译：使用模拟单克隆抗体的表位结合特性的癌症靶向的新方法

Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment

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