首页> 外文OA文献 >Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12VAL) peptide vaccination of a patient, recognize 12VAL-dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation

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Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12VAL) peptide vaccination of a patient, recognize 12VAL-dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation

机译：细胞毒性CD4 +和CD8 + T淋巴细胞，由患者的突变P21-RAS（12VAL）肽接种疫苗接种，识别存在于疫苗肽内的12VAL依赖性巢表位，并杀死携带这种突变的自体肿瘤细胞

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Marianne K. Gjertsen; Jens Bjørheim; Ingvil Saeterdal; June Myklebust; Gustav Gaudernack;
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年度 1997
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1. Cytotoxic CD8+ T cells recognize EBV antigen but poorly kill autologous EBV-infected B lymphoblasts: immunodominance is elicited by a peptide epitope that is presented at low levels in vitro. [J] . Shi Y, Smith KD, Kurilla MG, The Journal of Immunology: Official Journal of the American Association of Immunologists . 1997,第4期

机译：细胞毒性CD8 + T细胞识别EBV抗原，但杀死自体EBV感染的B淋巴母细胞的效果很差：免疫抗原是由体外呈低水平存在的肽表位引起的。
2. A parathyroid-hormone-related-protein (PTH-rP)-specific cytotoxic T cell response induced by in vitro stimulation of tumour-infiltrating lymphocytes derived from prostate cancer metastases, with epitope peptide-loaded autologous dendritic cells and low-dose IL-2 [J] . British Journal of Cancer . 2001,第11期

机译：甲状旁腺激素相关蛋白（PTH-rP）特异性细胞毒性T细胞反应，通过体外刺激载有抗原决定簇肽的自体树突状细胞和低剂量IL-2刺激前列腺癌转移灶衍生的肿瘤浸润淋巴细胞而诱导
3. Identification of the HLA-A24 peptide epitope within cytomegalovirus protein pp65 recognized by CMV-specific cytotoxic T lymphocytes. [J] . Masuoka M, Yoshimuta T, Hamada M, Viral immunology . 2001,第4期

机译：在巨细胞病毒蛋白pp65中被CMV特异性细胞毒性T淋巴细胞识别的HLA-A24肽表位的鉴定。
4. A parathyroid-hormone-related-protein (PTH-rP)-specific cytotoxic T cell response induced by in vitro stimulation of tumour-infiltrating lymphocytes derived from prostate cancer metastases with epitope peptide-loaded autologous dendritic cells and low-dose IL-2 [O] . P Correale, L Micheli, M T Del Vecchio, 2001

机译：甲状旁腺激素相关蛋白（PTH-rP）特异性细胞毒性T细胞反应通过体外刺激载有抗原决定簇肽的自体树突状细胞和低剂量IL-2刺激前列腺癌转移瘤衍生的肿瘤浸润淋巴细胞
5. Peptide Epitopes from the Wilms' Tumor 1 Oncoprotein Stimulate CD4+ and CD8+ T Cells That Recognize and Kill Human Malignant Mesothelioma Tumor Cells [O] . Rena J. May, Tao Dao, Javier Pinilla-Ibarz, 2007

机译：肽肿瘤的肽表位1癌蛋白刺激CD4 +和CD8 + T细胞，识别并杀死人恶性间皮瘤肿瘤细胞的肿瘤细胞

Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12VAL) peptide vaccination of a patient, recognize 12VAL-dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation

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