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Pre-event quality of life and its influence on the post-event quality of life among patients with ST elevation and non-ST elevation myocardial infarctions of a premier province of Sri Lanka

机译:事件前生命质量及其对斯里兰卡首屈一指省的圣升高和非St高程心肌梗死患者患者的事后生活质量的影响

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摘要

Abstract Background Pre-event Quality of Life (QOL) reflects the true social circumstances in which people live prior to the onset of myocardial infarctions. It is believed to be a predictor of the post-event QOL. The aim of this study was to describe the pre-event QOL and its influence on the post-event Quality of Life among patients with ST elevation (STEMI) and Non-ST elevation myocardial infarctions (NSTEMI) using Short Form-36 (SF-36), a generic QOL tool with 8 domains. Documented literature is rare in this regard in Sri Lanka, which is a lower-middle-income country. Methods A cross-sectional study with a 28-day post-discharge follow-up was carried out in 13 hospitals. Three hundred and forty-four patients who were diagnosed with STEMI or NSTEMI were recruited during the hospital stay. The pre-event QOL was measured using an interviewer-administered questionnaire which included the SF-36 QOL tool and medical details. Follow-up QOL was gathered using a questionnaire that was filled and posted back by participants. Of the recruited sample, 235 responded for the follow-up component. Analysis was conducted for associations between pre- and post-discharge QOL. Furthermore, comparisons were made between the STEMI and NSTEMI groups. Mann Whiney U test, Wilcoxon signed rank test and chi square test were used in the analysis. Results The post-event QOL was lower in seven out of eight domains than the pre-event QOL (p < 0.05). The NSTEMI group had more risk factors and a significantly lower pre-event QOL for seven domains (p  0.05) between the STEMI and NSTEMI groups. Post-discharge general-health QOL domain score was higher than the pre-MI score (p = 0.028) and was higher in the STEMI group compared to the NSTEMI group (p = 0.042). Regression analysis showed a significant beta coefficient between pre- and post-QOL for five domains in STEMI and for all domains in NSTEMI groups when adjusted for the disease severity. The R square values ranged from 12.3 to 62.3% for STEMI and 7.3 to 64.8% for NSTEMI. Conclusions Pre-event QOL is lower in the NSTEMI group compared to the STEMI group. Patients do not regain the previous QOL within one month post-discharge. Post-discharge QOL can be predicted by the pre-event QOL for most domains.
机译:摘要背景日事件前的生活质量(QOL)反映了人们在心肌梗死前居住的真实社会环境。它被认为是事件后QOL的预测因素。本研究的目的是描述ST升高(Stemi)和非St升高心肌梗死(NSTemi)的患者前QOL及其对事件后生活质量的影响,使用短的形式-36(SF- 36),具有8个域的通用QOL工具。在斯里兰卡的文献中,文献的文献很少见,这是一个中低收入国家。方法在13家医院进行28天后出院后续后的横截面研究。在住院期间招募了三百四十四名诊断患有STEMI或NSTEMI的患者。使用采访者管理的调查问卷测量前赛前QOL,其中包括SF-36 QOL工具和医疗细节。随访QOL使用参与者填写和发布后面的问卷收集。招募样本,后续组件的235次响应。进行分析,用于放电后QOL之间的关联。此外,在STEMI和NSTEMI组之间进行比较。 Mann Whiney U测试,在分析中使用了Wilcoxon签名等级测试和Chi方检验。结果八个域中的七个域外后的事后QOL比预先发生的QOL(P <0.05)较低。 Nstemi组在Stemi和Nstemi组之间具有更多的风险因素和显着降低的七个域的七个域(p 0.05)。放电后一般健康QOL结构域评分高于MI前评分(P = 0.028),与NSTemi组相比,STEMI组较高(P = 0.042)。回归分析显示在STEMI中的五个域和后QOL前和后QOL之间的显着β系数,并且在调整疾病严重程度时为NSTEMI组中的所有结构域。 r平方值的末端值为13.3%至62.3%,Nstemi的7.3%至64.8%。与Stemi组相比,Nstemi组预先发生前QOL较低。患者在放电后一个月内没有重新获得以前的QoL。放电后QOL可以通过前列QOL预测大多数域。

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