首页> 外文OA文献 >* LNA-Modified oligonucleotides targeting mRNA of dicer in pegylated colloidal nanoparticles with linked ABS against CD44 eradicate esophageal cancer stem cells (ECSC) by induction of PCD after inhibition of oncomir machinery

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* LNA-Modified oligonucleotides targeting mRNA of dicer in pegylated colloidal nanoparticles with linked ABS against CD44 eradicate esophageal cancer stem cells (ECSC) by induction of PCD after inhibition of oncomir machinery

机译：*通过在抑制oncomir机械后，通过诱导PCD与CD44的聚乙二醇化胶体纳米颗粒中的PEG化胶体纳米颗粒中的解酯纳米颗粒mRNA的LNA改性的寡核苷酸靶向。抑制oncomir机械后，通过诱导PCD来消除食管癌干细胞（ECSC）

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J. Giannios;
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年度 2011
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1. 713 POSTER Molecularly targeted immunochemotherapeutic formulation (SEVINA) composed of pegylated trispecific disulfide linked Fv (sdFv) targeting epitopes of EGFR, PTHrP and RANKL conjugated covalently with SATA to vinorelbine eradicated osteolytic metastases of multiple myeloma inhibiting proliferation of tumor associated and bone microvascular endothelial cells inducing ADCC, AMP and type I, II, III PCD [J] . J.Giannios, E.Michailakis, N.Alexandropulos European Journal of Cancer Supplements . 2007,第4期

机译：713 POSTER分子靶向免疫化学疗法制剂（SEVINA），由聚乙二醇化的三特异性二硫键联的Fv（sdFv）靶向EGFR，PTHrP和RANKL的抗原决定簇，与SATA共价结合到长春瑞滨上，消除了长春瑞滨清除多发性骨髓瘤的溶骨性转移，抑制了肿瘤相关细胞和骨微血管内皮细胞的增殖ADCC，AMP和I，II，III型PCD
2. CD44 targeted chemotherapy for co-eradication of breast cancer stem cells and cancer cells using polymeric nanoparticles of salinomycin and paclitaxel [J] . Muntimadugu Eameema, Kumar Rajendra, Saladi Shantikumar, Colloids and Surfaces, B. Biointerfaces . 2016,第Null期

机译：CD44靶向化疗，使用沙利霉素和紫杉醇的聚合物纳米粒子共同根除乳腺癌干细胞和癌细胞
3. Targeted eradication of gastric cancer stem cells by CD44 targeting USP22 small interfering RNA-loaded nanoliposomes [J] . Yang Feng, Zheng Zhi, Xue Xuchao, Future oncology . 2019,第3期

机译：通过CD44靶向USP22小干扰RNA负载RNA纳米脂质体的靶向消除胃癌干细胞
4. Targeting CD44 with nanoparticles in head and neck squamous cell carcinoma: A novel therapeutic strategy against cancer stem cells [D] . Thapa, Ranjeeta. 2016

机译：在头颈部鳞状细胞癌中以纳米粒子靶向CD44：针对癌症干细胞的新型治疗策略
5. Enhanced targeting of prostate cancer-initiating cells by salinomycin-encapsulated lipid-PLGA nanoparticles linked with CD44 antibodies [O] . Jun Wei, Jin Sun, Yu Liu -1

机译：与CD44抗体连接的沙利霉素包封的脂质PLGA纳米颗粒增强了对前列腺癌起始细胞的靶向性
6. Apoptotic effect of pegylated-nanoparticles of CDP bound to multitargeted sirna molecules against bmi1 and survivin conjugated with MIR-373 (termed as sevin-a) which target gastric cancer stem cells (GCSCS) overexpressing CD44 after circumvention of chemo [O] . J. N. Giannios, S. Delis 2011

机译：将CDP与MiR-373（称为Sevin-A称为Sevin-A缀合的BMI1和Survivin与MiR-373（称为Sevin-A）结合的凋亡效应靶向胃癌干细胞（GCSCs）。在Chemo的规避后过表达CD44
7. Cell Permeable Nanoconjugates of Shell-Crosslinked Knedel (SCK) and Peptide Nucleic Acids ('PNAs') with Uniquely Expressed or Over-Expressed mRNA Targeting Sequences for Early Diagnosis and Therapy of Cancer. [R] . Becker, M. L., Fang, H., Li, X., 2005

机译：具有独特表达或过度表达的mRNa靶向序列的壳交联克奈德（sCK）和肽核酸（'pNas'）的细胞可渗透纳米缀合物用于癌症的早期诊断和治疗。

* LNA-Modified oligonucleotides targeting mRNA of dicer in pegylated colloidal nanoparticles with linked ABS against CD44 eradicate esophageal cancer stem cells (ECSC) by induction of PCD after inhibition of oncomir machinery

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