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Nanocantilever based mass sensor integrated with CMOS circuitry

机译:基于纳米膜膜的质量传感器与CMOS电路集成

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摘要

We have demonstrated the successful integration of a cantilever based mass detector with standard CMOS circuitry. The purpose of the circuitry is to facilitate the readout of the cantilever's deflection in order to measure resonant frequency shifts of the cantilever. The principle and design of the mass detector are presented showing that miniaturization of such cantilever based resonant devices leads to highly sensitive mass sensors, which have the potential to detect single molecules. The design of the readout circuitry used for the first electrical characterization of an integrated cantilever is described in detail. The integration of the cantilever is a post processing module and the full process sequence is discussed. One of the main challenges during the fabrication of the cantilevers is sticktion of the cantilever to the bottom substrate after underclothing. Two dry release techniques were used to solve the problem, namely freeze-drying and resist-assisted release. The fabrication results of cantilevers defined by laser and E-beam lithography are shown. Finally, an AFM based characterization setup is presented and the electrical characterization of a laser-defined cantilever fully integrated with CMOS circuitry is demonstrated. The electrical characterization of the device shows that the resonant behavior of the cantilever depends on the applied voltages, which corresponds to theory.
机译:我们已经证明了基于悬臂的质量检测器与标准CMOS电路的成功集成。该电路的目的是便于读出悬臂的挠度,以便测量悬臂的共振频率偏移。提出了质量检测器的原理和设计,表明这种基于悬臂的谐振装置的小型化导致了高度敏感的质量传感器,该传感器具有检测单个分子的潜力。详细描述了用于集成悬臂的第一电气特性的读出电路的设计。悬臂的集成是一个后处理模块,并讨论了整个过程序列。悬臂制造过程中的主要挑战之一是在内衣后悬臂粘附到底部基底上。两种干脱模技术用于解决该问题,即冷冻干燥和抗蚀剂辅助脱模。显示了由激光和电子束光刻定义的悬臂的制造结果。最后,介绍了一种基于AFM的特性设置,并演示了与CMOS电路完全集成的激光定义的悬臂的电特性。器件的电气特性表明,悬臂的共振行为取决于所施加的电压,这与理论一致。

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