首页> 外文OA文献 >Proinflammatory Secreted Phospholipase A2 Type IIA (sPLA-IIA) Induces Integrin Activation through Direct Binding to a Newly Identified Binding Site (Site 2) in Integrins αvβ3, α4β1, and α5β1

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Proinflammatory Secreted Phospholipase A2 Type IIA (sPLA-IIA) Induces Integrin Activation through Direct Binding to a Newly Identified Binding Site (Site 2) in Integrins αvβ3, α4β1, and α5β1

机译：促炎性分泌的磷脂酶A2 IIa（SPLA-IIA）通过直接结合整合蛋白αvβ3，α4β1和α5β1的新鉴定的结合位点（位点2）诱导整联蛋白激活

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Masaaki Fujita; Kan Zhu; Chitose K. Fujita; Min Zhao; Kit S. Lam; Mark J. Kurth; Yoko K. Takada; Yoshikazu Takada;
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1. Stromal cell-derived factor-1 (CXCL12) activates integrins by direct binding to an allosteric ligand-binding site (site 2) of integrins without CXCR4 [J] . Masaaki Fujita, Parastoo Davari, Yoko K. Takada, The Biochemical Journal . 2018,第4期

机译：基质细胞衍生的因子-1（CXCL12）通过直接结合到没有CXCR4的整联蛋白的颠覆性配体结合位点（Site 2）直接结合整联蛋白
2. Secreted Phospholipase A2 Type IIA (sPLA2-IIA) Activates Integrins in an Allosteric Manner [J] . Yoshikazu Takada, Masaaki Fujita Advances in Experimental Medicine and Biology . 2017,第期

机译：分泌的磷脂酶A2 IIa（SPLA2-IIA）以变色方式激活整联蛋白
3. Characterization of suramin binding sites on the human group IIA secreted phospholipase A _2 by site-directed mutagenesis and molecular dynamics simulation [J] . Aragao E.A., Vieira D.S., Chioato L., Archives of Biochemistry and Biophysics . 2012,第1期

机译：通过定点诱变和分子动力学模拟表征人类IIA分泌磷脂酶A _2上的苏拉明结合位点
4. Molecular Modeling of Adsorption-Induced Denaturation of Integrin Binding Sites in Fibronectin [C] . Kerry Wilson, Steven J. Stuart, Andres J. Garcia, Annual meeting of the Society For Biomaterials . 2002

机译：纤连蛋白中吸附诱导的整合素结合位点变性的分子模型
5. Structure and function of the major platelet integrin alpha-IIb-beta-3 (GPIIb-IIIa complex): Effects of mutations on ligand binding and cellular signaling. [D] . Wang, Ronggang. 1996

机译：主要血小板整联蛋白α-IIb-β-3（GPIIb-IIIa复合物）的结构和功能：突变对配体结合和细胞信号传导的影响。
6. Proinflammatory Secreted Phospholipase A2 Type IIA (sPLA-IIA) Induces Integrin Activation through Direct Binding to a Newly Identified Binding Site (Site 2) in Integrins αvβ3 α4β1 and α5β1 [O] . Masaaki Fujita, Kan Zhu, Chitose K. Fujita, 2015

机译：促炎性分泌型IIA型磷脂酶A2（sPLA-IIA）通过直接结合至整合素αvβ3α4β1和α5β1中新鉴定的结合位点（位点2）诱导整合素激活。
7. Characterization of suramin binding sites on the human group IIA secreted phospholipase A2 by site-directed mutagenesis and molecular dynamics simulation [O] . Aragão Elisângela Aparecida, Vieira Davi Serradella, Chioato Lucimara, 2012

机译：通过定点诱变和分子动力学模拟表征IIA型人类分泌磷脂酶A2上的苏拉明结合位点

Proinflammatory Secreted Phospholipase A2 Type IIA (sPLA-IIA) Induces Integrin Activation through Direct Binding to a Newly Identified Binding Site (Site 2) in Integrins αvβ3, α4β1, and α5β1

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