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ATNT-12PHASE I, TWO-STAGE, OPEN-LABEL, DOSE-ESCALATION STUDY OF BUPARLISIB (BKM120) IN COMBINATION WITH ADJUVANT TEMOZOLOMIDE (TMZ) AND WITH CONCOMITANT RADIATION THERAPY (RT) AND TMZ IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM)

机译：atnt-12phase i，两阶段，开放标签，对Buptlisib（bkm120）的升级与佐剂替替莫唑胺（TMZ）和新诊断的胶质母细胞瘤（GBM）的伴随的放射治疗（RT）和TMZ组合

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Jordi Rodon; Mark Rosenthal; Warren Mason; Pedro Perez Segura; Joseph T. Beck; Holger Hirte; John F. DeGroot; Lucia Trandafir; Nathalie Pognan; Lin Yang; Charu Kanwal; Patrick Y. Wen;
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1. A Phase 2 Trial of Neoadjuvant Temozolomide (TMZ) Followed By Accelerated Hypofractionated Radiation Therapy (AHRT) and TMZ Followed By Adjuvant TMZ in Patients with Newly Diagnosed Glioblastoma (GBM): Long Term Survival and Toxicity Analysis [J] . Shenouda G., Souhami L., Petrecca K., International Journal of Radiation Oncology, Biology, Physics . 2018 ,第3Suppla期

机译：Neoadjuvant Temozolomide（TMZ）的2阶段试验，然后加速低次级的放射治疗（AHRT）和TMZ，然后在新诊断的胶质母细胞瘤（GBM）患者中进行佐剂TMZ：长期存活和毒性分析
2. EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma. [J] . Brandes AA, Stupp R, Hau European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2010 ,第2期

机译：EORTC研究26041-22041：在新诊断的胶质母细胞瘤中，伴有替莫唑胺（TMZ）和放疗（PTK）与PTK787 / ZK222584（PTK / ZK）进行的I / II期研究。
3. 311 Temozolomide (TMZ) combined with radiotherapy (RT) versus radiotherapy (RT) alone in newly diagnosed glioblastoma multiforme (GBM): A randomized phase III study [J] . H.Athanassiou, M.Synodinou, E.Maragoudakis, European Journal of Cancer Supplements . 2003 ,第5期

机译：311替莫唑胺（TMZ）联合放疗（RT）与单独放疗（RT）在新诊断的多形性胶质母细胞瘤（GBM）中的应用：一项随机III期研究
4. ATNT-12PHASE I TWO-STAGE OPEN-LABEL DOSE-ESCALATION STUDY OF BUPARLISIB (BKM120) IN COMBINATION WITH ADJUVANT TEMOZOLOMIDE (TMZ) AND WITH CONCOMITANT RADIATION THERAPY (RT) AND TMZ IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM) [O] . Jordi Rodon, Mark Rosenthal, Warren Mason, 2015

机译：新诊断的胶质母细胞瘤（GBM）患者中BUPARLISIB（BKM120）与辅助性替莫唑胺（TMZ）联合放疗（RT）和TMZ联合进行的ATNT-12阶段一期两阶段开放剂量剂量研究
5. A Phase 2 Trial of Neoadjuvant Temozolomide (TMZ) Followed By Accelerated Hypofractionated Radiation Therapy (AHRT) and TMZ Followed By Adjuvant TMZ in Patients with Newly Diagnosed Glioblastoma (GBM): Long Term Survival and Toxicity Analysis [O] . G. Shenouda, L. Souhami, K. Petrecca, 2018

机译：Neoadjuvant Temozolomide（TMZ）的2阶段试验，然后加速低次级的放射治疗（AHRT）和TMZ，然后在新诊断的胶质母细胞瘤（GBM）患者中进行佐剂TMZ：长期存活和毒性分析

ATNT-12PHASE I, TWO-STAGE, OPEN-LABEL, DOSE-ESCALATION STUDY OF BUPARLISIB (BKM120) IN COMBINATION WITH ADJUVANT TEMOZOLOMIDE (TMZ) AND WITH CONCOMITANT RADIATION THERAPY (RT) AND TMZ IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM)

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