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A systems biology approach to understanding the function of 5T4 oncofetal glycoprotein in ovarian cancer and the preclinical effectiveness of a 5T4 antibody drug conjugate

机译：一种理解5T4幼特区糖蛋白在卵巢癌中的功能的系统生物学方法及5T4抗体药物缀合物的临床前效果

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Y Louise Wan; Adam Stevens; Lynne Hampson; Henry Kitchener; Peter Stern;
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1. Combination Treatment with an Antibody-Drug Conjugate (A1mcMMAF) Targeting the Oncofetal Glycoprotein 5T4 and Carboplatin Improves Survival in a Xenograft Model of Ovarian Cancer (vol 14, pg 465, 2019) [J] . Wan Y. Louise, Sapra Puja, Bolton James, Targeted oncology . 2019,第6期

机译：用抗体 - 药物缀合物（A1MCMMAF）的组合处理靶向幼特糖蛋白5T4和卡铂改善卵巢癌的异种移植模型中的存活（Vol 14，PG 465,2019）
2. Combination Treatment with an Antibody-Drug Conjugate (A1mcMMAF) Targeting the Oncofetal Glycoprotein 5T4 and Carboplatin Improves Survival in a Xenograft Model of Ovarian Cancer [J] . Wan Y. Louise, Sapra Puja, Bolton James, Targeted oncology . 2019,第4期

机译：用抗体 - 药物缀合物（A1MCMMAF）的组合处理靶向幼丙蛋白糖蛋白5T4和卡铂改善了卵巢癌的异种移植模型中的存活
3. Targeting the 5T4 oncofetal glycoprotein with an antibody drug conjugate (A1mcMMAF) improves survival in patient-derived xenograft models of acute lymphoblastic leukemia [J] . Owen J. McGinn, Shekhar Krishnan, Jean-Pierre Bourquin, Haematologica . 2017,第6期

机译：用抗体药物偶联物（A1mcMMAF）靶向5T4胎粪糖蛋白可提高患者来源的急性淋巴细胞白血病异种移植模型的存活率
4. Profiling of Ovarian Cancer Reveals Common Features Shared by Sub-types of Ovarian Cancer: A network biology approach towards finding therapeutic drug targets [C] . Rinki Singh, Anup Som International Conference on Bioinformatics and Systems Biology . 2018

机译：剖析卵巢癌揭示了卵巢癌亚型共有的共同特征：寻找治疗药物靶点的网络生物学方法
5. Applications of chemical biology in drug discovery and systems biology: Fragment-based design of histone deacetylase inhibitors & A chemical approach to understanding polysaccharide biosynthesis and protein glycosylation. [D] . Woodward, Robert L., Jr. 2010

机译：化学生物学在药物发现和系统生物学中的应用：基于片段的组蛋白脱乙酰基酶抑制剂的设计和一种了解多糖生物合成和蛋白质糖基化的化学方法。
6. Combination Treatment with an Antibody–Drug Conjugate (A1mcMMAF) Targeting the Oncofetal Glycoprotein 5T4 and Carboplatin Improves Survival in a Xenograft Model of Ovarian Cancer [O] . Y. Louise Wan, Puja Sapra, James Bolton, -1

机译：靶向癌胚糖蛋白5T4和卡铂的抗体-药物偶联物（A1mcMMAF）的联合治疗可改善卵巢癌异种移植模型的存活率。
7. Correction to: Combination Treatment with an Antibody–Drug Conjugate (A1mcMMAF) Targeting the Oncofetal Glycoprotein 5T4 and Carboplatin Improves Survival in a Xenograft Model of Ovarian Cancer [O] . Y. Louise Wan, Puja Sapra, James Bolton, 2019

机译：校正：用抗体 - 药物缀合物（A1mCMMAF）的组合处理靶向幼特糖蛋白5t4和卡铂改善卵巢癌的异种移植模型中的存活

A systems biology approach to understanding the function of 5T4 oncofetal glycoprotein in ovarian cancer and the preclinical effectiveness of a 5T4 antibody drug conjugate

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