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Standard Polymeric Formula Tube Feeding in Neurologically Impaired Children: A Five-Year Retrospective Study

机译:在神经障碍儿童中喂养标准聚合物配方管:五年的回顾性研究

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摘要

Malnutrition is frequent in neurologically impaired (NI) children. Enteral feeding via gastrostomy tube is increasingly being used to provide adequate nutrition. Our aim was to assess the outcomes of exclusive gastrostomy tube feeding with standard polymeric formula in children with NI, severe oro-motor dysfunction, and malnutrition, and to investigate the role of the underlying NI-associated disease. A five-year retrospective study from January 2013 to November 2017 was conducted. The primary aim was to assess the nutritional outcomes of exclusive gastrostomy tube feeding with standard polymeric formula in malnourished NI children. The secondary aim was to investigate gastrostomy complications and the impact of the underlying NI-associated disease on the nutritional outcomes. We enrolled 110 consecutive children with NI. Of these patients, 34.5% (N = 38) were categorized as malnourished and started exclusive enteral feeding with a standard (1.0 kcal/mL) polymeric formula (Nutrini, Nutricia) after percutaneous endoscopic gastrostomy (PEG) placement. Seventy-three percent of patients (N = 28) had cerebral palsy (CP); other diagnoses included metabolic (13%, N = 5) and genetic (13%, N = 5) diseases. Tricep skinfold thickness had significantly improved in all patients at 12-months follow-up, while body weight and body mass index showed significant increases mainly in children with CP. No serious complications occurred. We found that standard polymeric formula via gastrostomy tube represents a safe and efficient nutritional intervention in children with NI and malnutrition.
机译:营养不良是神经功能受损(NI)儿童频繁。经由胃造口管肠道喂养越来越多地被用来提供足够的营养。我们的目的是评估独家胃造口管饲与儿童标准聚合配方与NI,严重的口运动功能障碍,和营养不良的结果,并调查底层NI相关疾病的作用。一个为期五年的回顾性研究,从2013年1月至2017年11月被进行。的主要目的是评估在营养不良儿童的NI独家胃造口管饲以标准聚合物配方的营养效果。次要目的是调查胃造口并发症和底层NI-相关疾病对营养状况的影响。我们招收110个连续小儿NI。在这些患者中,34.5%(N = 38)被归类为营养不良和开始独家肠饲以标准(1.0千卡/ mL)的聚合式(Nutrini,纽迪希亚)经皮内镜下胃造瘘术(PEG)放置。患者百分之七十三(N = 28)有脑瘫(CP);其他诊断包括代谢(13%,N = 5)和遗传(13%,N = 5)的疾病。三头肌皮褶厚度已在12个月的随访,所有患者显著改善,而体重和身体质量指数显示主要与脑瘫儿童显著上升。无严重并发症。我们发现通过胃管这一标准聚合配方代表了与NI和营养不良儿童的安全和有效的营养干预。

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