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Negative cell cycle regulator 14-3-3σ stabilizes p27 Kip1 by inhibiting the activity of PKB/Akt

机译：阴性细胞周期调节器14-3-3σ通过抑制PKB / AKT的活性来稳定P27 KIP1

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H Yang; Y Zhang; R Zhao; Y-Y Wen; K Fournier; H-B Wu; H-Y Yang; J Diaz; C Laronga; M-H Lee;
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1. Negative cell cycle regulator 14-3-3|[sigma]| stabilizes p27 Kip1 by inhibiting the activity of PKB|[sol]|Akt [J] . H Yang, Y Zhang, R Zhao, Oncogene . 2006 ,第33期

机译：负细胞周期调节剂14-3-3 |σ|通过抑制PKB | [sol] | Akt的活性来稳定p27 Kip1
2. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. [J] . Shin I, Yakes FM, Rojo F, Nature medicine . 2002 ,第10期

机译：PKB / Akt通过苏氨酸157处p27（Kip1）的磷酸化及其细胞定位的调节来介导细胞周期进程。
3. ex, some cell cycle regulators (cyclin D1, cyclin E, p34/cdc2, p27/kip1), and cell proliferation. There was a statistically significant direct correlation between pAkt expression (both cytoplasmatic and nuclear) and depth of infiltration of the tumor, number of infiltrated lymph nodes and p34/cdc2 expression, and between prevalently nuclear pAkt and cyclin D1 and cyclin E. Conversely, there was a significant inverse correlation between nuclear pAkt and apoptotic index and between cytoplasmatic a [J] . Molecular cancer research: MCR . 2009 ,第9期

机译：例如，一些细胞周期调节剂（cyclin D1，cyclin E，p34 / cdc2，p27 / kip1）和细胞增殖。在pAkt表达（细胞质和核）与肿瘤浸润深度，浸润的淋巴结数目和p34 / cdc2表达之间，以及在核pAkt与cyclin D1和cyclin E之间，存在统计学上的显着直接相关性。与核pAkt和凋亡指数之间以及细胞质
4. The Development of p27~(kip1) Nanoliposome Gene Delivery System and Its Growth Inhibition Effects on Human Lung Caner Cells [C] . Hongwei Zhang, Xun Sun, Ling Zhang, Controlled Release Society Annual Meeting and Exposition . 2007

机译：p27〜（kip1）纳米脂质体基因传递系统的开发及其对人肺癌细胞的生长抑制作用
5. A biochemical analysis of the cell cycle specific degradation of the CDK inhibitor p27(kip1). [D] . Nguyen, Hoang. 2002

机译：CDK抑制剂p27（kip1）的细胞周期特异性降解的生化分析。
6. Downregulation of cyclin-dependent kinase 2 activity and cyclin A promoter activity in vascular smooth muscle cells by p27(KIP1) an inhibitor of neointima formation in the rat carotid artery. [O] . D Chen, K Krasinski, A Sylvester, 1997

机译：p27（KIP1）是大鼠颈动脉新内膜形成的抑制剂下调了血管平滑肌细胞中细胞周期蛋白依赖性激酶2活性和细胞周期蛋白A启动子的活性。
7. ERK Phosphorylates p66shcA on Ser36 and Subsequently Regulates p27^kip1 Expression via the Akt-FOXO3a Pathway: Implication of p27^kip1 in Cell Response to Oxidative Stress [O] . Hu Yuanyu, Wang Xueying, Zeng Li, 2005

机译：ERK磷酸化Ser36上的p66shcA，并随后通过Akt-FOXO3a途径调节p27 ^ kip1表达：p27 ^ kip1在细胞对氧化应激反应中的意义

Negative cell cycle regulator 14-3-3σ stabilizes p27 Kip1 by inhibiting the activity of PKB/Akt

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