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Preparation of Hydroxyapatite Scaffold using Luffa Cylindrica Sponge as Template

机译:使用Luffa Comindrica海绵作为模板制备羟基磷灰石脚手架

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摘要

Hydroxyapatite (HA) scaffold has been widely applied in the biomedical field especially for bone implants. The purpose of this research is to determine the influence of dispersant addition and stirring time on HA scaffold which formed using gambas sponges as a template. HA slurry was made by mixing 10 grams of HA, 12 grams of aquadest, 0,2; 0,25; 0,3 grams of Darvan 821A and 1 gram of sago. The slurry was impregnated into Luffa cylindrica sponges. The sample then dried at 110oC for 3 hours. The green bodies were burned at 600oC for 1 hour and followed by sintering at 1250oC for 1 hour. The results showed that the addition of dispersant and increasing of stirring time lead to smaller porosity and shrinkage. In addition 0,2; 0,25; and 0,3 grams dispersant, the resulting porosity in the range of 63,85-70,78%; 58,74-70,35%; and 53,42-69,66%. Shrinkage 39,43-53,71%; 27,75-50,68%; and 13,61-41,25%. Compressive strength 0,61-1,05 MPa; 2,88-3,81MPa; and 0,52-2,96 MPa. The macroporous and microporous average pore sized was 50 µm dan 5 µm.
机译:羟基磷灰石(HA)支架已广泛应用于生物医学领域,特别是对于骨植入物。该研究的目的是确定分散剂添加和搅拌时间对使用冈比卡海绵作为模板形成的HA支架的影响。 HA浆液是通过混合10克HA,12克AQUAMAT,0.2; 0,25; 0,3克Darvan 821a和1克的佐贺。将浆液浸渍到Luffa Comwindrica海绵中。然后将样品在110℃下干燥3小时。绿色体在600℃下烧1小时,然后在1250℃下烧结1小时。结果表明,添加分散剂和搅拌时间的增加导致较小的孔隙率和收缩。另外0,2; 0,25;和0.3克分散剂,所得孔隙率在63,85-70,78%的范围内; 58,74-70,35%;和53,42-69,66%。收缩39,43-53,71%; 27,75-50,68%;和13,61-41,25%。抗压强度0,61-105 MPa; 2,88-3,81MPA;和0,52-2,96 MPa。大孔和微孔的平均孔径为50μmdan5μm。

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