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Acylated and Unacylated Ghrelin Promote Proliferation and Inhibit Apoptosis of Pancreatic β-Cells and Human Islets: Involvement of 3′,5′-Cyclic Adenosine Monophosphate/Protein Kinase A, Extracellular Signal-Regulated Kinase 1/2, and Phosphatidyl Inositol 3-Kinase/Akt Signaling

机译：酰化和未加工的Ghrelin促进增殖和抑制胰腺β细胞的凋亡和人体胰岛：3'，5'-环状腺苷一磷酸盐/蛋白激酶A，细胞外信号调节激酶1/2和磷脂酰肌醇3-激酶/ AKT信号传导

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Riccarda Granata; Fabio Settanni; Luigi Biancone; Letizia Trovato; Rita Nano; Federico Bertuzzi; Silvia Destefanis; Marta Annunziata; Monica Martinetti; Filomena Catapano; Corrado Ghè; Jorgen Isgaard; Mauro Papotti; Ezio Ghigo; Giampiero Muccioli;
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1. The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways [J] . E. Favaro, R. Granata, I. Miceli, Diabetologia: clinical and experimental diabetes and metabolism . 2012,第4期

机译：ghrelin基因产物和exendin-4通过磷酸肌醇3-激酶/ Akt，细胞外信号相关激酶（ERK）1/2和cAMP /蛋白激酶A（PKA）信号通路促进高血糖条件下人胰岛内皮细胞的存活
2. Heat shock protein 27 phosphorylation in the proliferation and apoptosis of human umbilical vein endothelial cells induced by high glucose through the phosphoinositide 3-kinase/Akt and extracellular signal-regulated kinase 1/2 pathways [J] . Chen Hai-Feng, Liu Shu-Juan, Chen Gang Molecular medicine reports . 2015,第2期

机译：高糖通过磷酸肌醇3-激酶/ Akt和细胞外信号调节激酶1/2途径诱导人脐静脉内皮细胞增殖和凋亡中的热休克蛋白27磷酸化
3. Effect of phosphatidyl inositol 3-kinase, extracellular signal-regulated kinases 1/2, and p38 mitogen-activated protein kinase inhibition on osteogenic differentiation of muscle-derived stem cells. [J] . Payne KA, Meszaros LB, Phillippi JA, Tissue engineering, Part A . 2010,第12期

机译：磷脂酰肌醇3-激酶，细胞外信号调节激酶1/2和p38丝裂原活化蛋白激酶抑制作用对肌肉衍生干细胞成骨分化的影响。
4. Caspase Activation and Extracellular Signal-Regulated Kinase/Akt Inhibition Were Involved in Luteolin-Induced Apoptosis in Lewis Lung Carcinoma Cells [C] . JIN-HYUNG KIM, EUN-OK LEE, HYO-JUNG LEE, Meeting on Cell Signaling World: Signal Transduction Pathways as Therapeutic Targets . 2007

机译：半胱氨酸天冬氨酸蛋白酶激活和细胞外信号调节激酶/ Akt抑制涉及路易斯-肺癌细胞中木犀草素诱导的细胞凋亡。
5. Signaling pathway from the A(2B) adenosine receptor to extracellular signal-regulated kinases (ERK1/2) in human umbilical vein endothelial cells (HUVEC) and its role in HUVEC proliferation [D] . Fang, Ying 2006

机译：从A（2B）腺苷受体到人脐静脉内皮细胞（HUVEC）中细胞外信号调节激酶（ERK1 / 2）的信号通路及其在HUVEC增殖中的作用
6. The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions through phosphoinositide 3-kinase/Akt extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways [O] . E. Favaro, R. Granata, I. Miceli, -1

机译：ghrelin基因产物和exendin-4通过磷酸肌醇3-激酶/ Akt细胞外信号相关激酶（ERK）1/2和cAMP /蛋白激酶A（PKA）信号通路促进高血糖条件下人胰岛内皮细胞的存活
7. The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways [O] . E. Favaro, R. Granata, I. Miceli, 2012

机译：ghrelin基因产物和exendin-4通过磷酸肌醇3-激酶/ Akt，细胞外信号相关激酶（ERK）1/2和cAMP /蛋白激酶A（PKA）信号通路促进高血糖条件下人胰岛内皮细胞的存活
8. Hepatocyte Growth Factor Inhibits Apoptosis by the Profibrotic Factor Angiotensin II via Extracellular Signal-regulated Kinase 1/2 in Endothelial Cells and Tissue Explants [R] . Lee, Y. H., Marquez, A. P., Mungunsukh, O., 2010

机译：肝细胞生长因子通过细胞外信号调节激酶1/2在内皮细胞和组织外植体中抑制促纤维化因子血管紧张素II的凋亡

Acylated and Unacylated Ghrelin Promote Proliferation and Inhibit Apoptosis of Pancreatic β-Cells and Human Islets: Involvement of 3′,5′-Cyclic Adenosine Monophosphate/Protein Kinase A, Extracellular Signal-Regulated Kinase 1/2, and Phosphatidyl Inositol 3-Kinase/Akt Signaling

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