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Late Treatment with a Protective Antigen–Directed Monoclonal Antibody Improves Hemodynamic Function and Survival in a Lethal Toxin–Infused Rat Model of Anthrax Sepsis

机译：用保护性抗原定向的单克隆抗体治疗改善血液动力学功能和在亚鼻败血症的致死毒素染发剂大鼠模型中存活

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Xizhong Cui; Yan Li; Mahtab Moayeri; Gil H. Choi; G. M. Subramanian; Xuemei Li; Michael Haley; Yvonne Fitz; Jing Feng; Steven M. Banks; Stephen H. Leppla; Peter Q. Eichacker;
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1. Late treatment with a protective antigen-directed monoclonal antibody improves hemodynamic function and survival in a lethal toxin-infused rat model of anthrax sepsis. [J] . Cui X, Li Y, Moayeri M, The Journal of Infectious Diseases . 2005,第3期

机译：用保护性抗原指导的单克隆抗体进行的后期治疗可改善在注入炭疽的脓毒症致死大鼠模型中的血流动力学功能和存活率。
2. Delayed treatment with W1-mAb, a chimpanzee-derived monoclonal antibody against protective antigen, reduces mortality from challenges with anthrax edema or lethal toxin in rats and with anthrax spores in mice. [J] . Altaweel L, Chen Z, Moayeri M, Critical care medicine . 2011,第6期

机译：W1-mAb（一种来自黑猩猩的保护性抗原单克隆抗体）的延迟治疗可降低大鼠炭疽水肿或致命毒素以及小鼠炭疽孢子的攻击所致的死亡率。
3. Enhancement of Anthrax Lethal Toxin Cytotoxicity: a Subset of Monoclonal Antibodies against Protective Antigen Increases Lethal Toxin-Mediated Killing of Murine Macrophages [J] . Nehal Mohamed, Juan Li, Claudia S. Ferreira, Infection and immunity . 2004,第6期

机译：炭疽致死毒素细胞毒性增强：抗保护性抗原的单克隆抗体子集增加了致死毒素介导的小鼠巨噬细胞的杀伤。
4. Demonstrating biomanufacturing comparability of therapeutic glycosylated monoclonal antibodies through identification of N-linked glycans by directed multi-stage mass spectrometry oligosaccharide profiling [C] . Gina Eagle, Shuuichi Nakaya, Daniel Spencer, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：通过定向多阶段质谱寡糖分析通过鉴定治疗性糖基化单克隆抗体的生物制造能力通过鉴定N键聚乙醇
5. Lipid Composition and pH Regulate Anthrax Toxin Protective Antigen Behavior and Lethal Factor Binding [D] . Kalu, Nnanya U. 2018

机译：脂质组成和pH值调节炭疽毒素保护性抗原的行为和致命因子的结合。
6. Delayed treatment with W1-mAb a chimpanzee-derived monoclonal antibody against protective antigen reduces mortality from challenges with anthrax edema or lethal toxin in rats and with anthrax spores in mice [O] . Laith Altaweel, Zhaochun Chen, Mahtab Moayeri, -1

机译：用W1-mAb延迟治疗一种针对保护性抗原的黑猩猩衍生的单克隆抗体从大鼠和小鼠中的炭疽孢子与炭疽水肿或致命毒素的挑战降低了死亡率
7. In Vitro and In Vivo Characterization of Anthrax Anti-Protective Antigen and Anti-Lethal Factor Monoclonal Antibodies after Passive Transfer in a Mouse Lethal Toxin Challenge Model To Define Correlates of Immunity▿ [O] . Staats, Herman F., Alam, S. Munir, Scearce, Richard M., 2007

机译：小鼠致命毒素挑战模型中被动转移后炭疽抗保护抗原和抗致死因子单克隆抗体的体外和体内表征，以定义免疫相关性
8. Production and Characterization of Monoclonal Antibodies Against the Protective Antigen Component of Bacillus anthracis Toxin [R] . Little, S. F., Leppla, S. H., Cora, E. 1988

机译：抗炭疽杆菌毒素保护性抗原成分单克隆抗体的制备及鉴定

Late Treatment with a Protective Antigen–Directed Monoclonal Antibody Improves Hemodynamic Function and Survival in a Lethal Toxin–Infused Rat Model of Anthrax Sepsis

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