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CLICK-MS and MASTER-2 Phase IV trial design: cladribine tablets in suboptimally controlled relapsing multiple sclerosis

机译：点击 - MS和Master-2相位IV试验设计：Cladribine片剂在次优控制复发多发性硬化症

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Augusto A Miravalle; Joshua Katz; Derrick Robertson; Brooke Hayward; Danielle E Harlow; Lori A Lebson; Jacob A Sloane; Ann D Bass; Edward J Fox;
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1. Safety and efficacy of cladribine tablets in patients with relapsing-remitting multiple sclerosis: Results from the randomized extension trial of the CLARITY study [J] . Giovannoni Gavin, Sorensen Per Soelberg, Cook Stuart, Multiple sclerosis: clinical and laboratory research . 2018,第12期

机译：Cladribine片剂在复发延伸患者患者中的安全性和有效性：清晰度研究的随机扩展试验结果
2. Treatment-emergent adverse events occurring early in the treatment course of cladribine tablets in two phase 3 trials in multiple sclerosis [J] . Jiwon Oh, Bryan Walker, Gavin Giovannoni, Multiple Sclerosis Journal ?C Experimental, Translational and Clinical . 2021,第3期

机译：治疗 - 在多个硬化症中的两阶段3次试验中，在克拉酮药片的治疗过程中发生的治疗发生不良事件
3. A placebo-controlled trial of oral cladribine for relapsing multiple sclerosis. [J] . Giovannoni G, Comi G, Cook The New England journal of medicine . 2010,第5期

机译：口服克拉屈滨治疗复发性多发性硬化症的安慰剂对照试验。
4. Microstructural Modulations in the Hippocampus Allow to Characterizing Relapsing-Remitting Versus Primary Progressive Multiple Sclerosis [C] . Lorenza Brusini, Ilaria Boscolo Galazzo, Muge Akinci, International Workshop on Brain-Lesion;Medical Image Computing and Computer Assisted Intervention Conference . 2020

机译：海马中的微观结构调制允许表征复发 - 延长与初级进步多发性硬化
5. Processing speed and working memory training in multiple sclerosis: A blinded randomized controlled trial. [D] . Hancock, Laura Mitchell. 2013

机译：多发性硬化症的处理速度和工作记忆训练：一项双盲随机对照试验。
6. A one-year prospective randomized placebo-controlled quadruple-blinded phase II safety pilot trial of combination therapy with interferon beta-1a and mycophenolate mofetil in early relapsing–remitting multiple sclerosis (TIME MS) [O] . Gina M. Remington, Katherine Treadaway, Teresa Frohman, 2010

机译：一项为期一年的前瞻性随机安慰剂对照四盲II期安全性早期试验联合干扰素β-1a和霉酚酸酯在早期复发-缓解的多发性硬化症（TIME MS）中联合使用
7. Safety and efficacy of cladribine tablets in patients with relapsing–remitting multiple sclerosis: Results from the randomized extension trial of the CLARITY study [O] . Gavin Giovannoni, Per Soelberg Sorensen, Stuart Cook, 2017

机译：Cladribine片剂在复发延长多发性硬化症患者中的安全性和有效性：清晰度研究的随机扩展试验结果

CLICK-MS and MASTER-2 Phase IV trial design: cladribine tablets in suboptimally controlled relapsing multiple sclerosis

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