Anti-ErbB3/Anti-IGF-1R Bispecific Monoclonal Antibody MM-141

机译：抗ERBB3 /抗IGF-1R双特异性单克隆抗体MM-141

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1. Istiratumab (MM-141), A Bispecific Antibody Targeting IGF-1R and ERBB3, Potentiates the Activity of Standard of Care Chemotherapy in In Vivo Models of Ewing Sarcoma [J] . Curley M., Yannatos I., Camblin A., Pediatric blood & cancer . 2016,第Suppla3期

机译：Istiratumab（MM-141），一种靶向IGF-1R和ERBB3的双特异性抗体，可增强尤文氏肉瘤体内模型中护理化学疗法的标准活性。
2. MM-141, an IGF-IR- and ErbB3-Directed Bispecific Antibody, Overcomes Network Adaptations That Limit Activity of IGF-IR Inhibitors [J] . Fitzgerald Jonathan B., Johnson Bryan W., Baum Jason, Molecular cancer therapeutics . 2014,第2期

机译：MM-141，一种IGF-IR和ErbB3指导的双特异性抗体，克服了限制IGF-IR抑制剂活性的网络适应性
3. A phase 1 study of MM-141, a novel tetravalent monoclonal antibody targeting IGF-1R and ErbB3, in relapsed or refractory solid tumors [J] . Isakoff S., Bahleda R., Saleh M., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2016,第Null期

机译：MM-141，一种靶向IGF-1R和ErbB3的新型四价单克隆抗体，在复发或难治性实体瘤中的一期研究
4. Platform Method for Identity and Characterization of Therapeutic Monoclonal and Bispecific Antibodies by Intact and Reduced Mass Spectrometry [C] . Richard Seipert, Lisa Patterson, George Tsui, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：通过完整和降低质谱法的治疗单克隆和双特异性抗体的特性和表征平台方法
5. Development of bispecific monoclonal antibodies and their applications in ultrasensitive virus ELISA; phage display technology and viral purification [D] . Liu, Fei 1999

机译：双特异性单克隆抗体的开发及其在超敏病毒ELISA中的应用；噬菌体展示技术和病毒纯化
6. Combining Anti-ERBB3 Antibodies Specific for Domain I and Domain III Enhances the Anti-Tumor Activity over the Individual Monoclonal Antibodies [O] . Jimson W. D’Souza, Smitha Reddy, Lisa E. Goldsmith, -1

机译：结合特异性针对域I和域III的抗ERBB3抗体增强了单个肿瘤单抗的抗肿瘤活性
7. Combining anti-ERBB3 antibodies specific for domain I and domain III enhances the anti-tumor activity over the individual monoclonal antibodies. [O] . Jimson W D'Souza, Smitha Reddy, Lisa E Goldsmith, 2014

机译：结合对结构域I和结构域III特异的抗ERBB3抗体增强了对单个单克隆抗体的抗肿瘤活性。

Anti-ErbB3/Anti-IGF-1R Bispecific Monoclonal Antibody MM-141

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