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Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells

机译：色氨酸32介导的SOD1聚集在活细胞中通过嘧啶样化合物衰减

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Edward Pokrishevsky; Luke McAlary; Natalie E. Farrawell; Beibei Zhao; Mine Sher; Justin J. Yerbury; Neil R. Cashman;
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1. Tryptophan?32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells [J] . Edward Pokrishevsky, Luke McAlary, Natalie E. Farrawell, Scientific reports. . 2018,第1期

机译：色氨酸α？32介导的SOD1聚集在活细胞中通过嘧啶样化合物衰减
2. Substantially elevating the levels of alpha B-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation [J] . Xu Guilian, Fromholt Susan, Ayers Jacob I., Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2015,第3期

机译：大幅提高突变型SOD1小鼠脊髓运动神经元中的αB-晶状体蛋白水平不会明显延迟麻痹或减弱突变型蛋白的聚集
3. Susceptibility of Mutant SOD1 to Form a Destabilized Monomer Predicts Cellular Aggregation and Toxicity but Not In vitro Aggregation Propensity [J] . Luke McAlary, J. Andrew Aquilina, Justin J. Yerbury Frontiers in Neuroscience . 2016,第2016期

机译：突变的SOD1形成不稳定单体的敏感性预测细胞聚集和毒性，而不是体外聚集倾向。
4. Attenuation of neuronal cell death by SOD1 is associated with extracellular signal-regulated kinase after transient focal cerebral ischemia in mice [C] . Nobuo Noshita, Takeshi Hayashi, Atsushi Saito, International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia . 2003

机译：SOD1的神经元细胞死亡的衰减与小鼠瞬时焦点脑缺血后细胞外信号调节激酶有关
5. Arylsulfanyl Pyrazolones Block Mutant SOD1 Aggregation and have Potential Application for the Treatment of Amyotrophic Lateral Sclerosis. [D] . Chen, Tian. 2011

机译：芳硫基吡唑啉酮可阻止突变型SOD1聚集，并可能在肌萎缩性侧索硬化症的治疗中应用。
6. Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells [O] . Edward Pokrishevsky, Luke McAlary, Natalie E. Farrawell, -1

机译：色氨酸32介导的SOD1聚集被活细胞中的嘧啶样化合物减弱
7. Spinal cord homogenates from SOD1 familial amyotrophic lateral sclerosis induce SOD1 aggregation in living cells. [O] . Edward Pokrishevsky, Ran Ha Hong, Ian R Mackenzie, 2017

机译：来自sOD1家族性肌萎缩侧索硬化的脊髓匀浆诱导活细胞中的sOD1聚集。

Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells

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