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Integrated Synthesis and Testing of Substituted Xanthine Based DPP4 Inhibitors: Application to Drug Discovery

机译：基于替代黄嘌呤的DPP4抑制剂的综合合成和测试：应用于药物发现

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Werngard Czechtizky; Jüergen Dedio; Bimbisar Desai; Karen Dixon; Elizabeth Farrant; Qixing Feng; Trevor Morgan; David M. Parry; Manoj K. Ramjee; Christopher N. Selway; Thorsten Schmidt; Gary J. Tarver; Adrian G. Wright;
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1. Integrated Synthesis and Testing of Substituted Xanthine Based DPP4 Inhibitors: Application to Drug Discovery [J] . Werngard Czechtizky, Ju?ergen Dedio, Bimbisar Desai ACS medicinal chemistry letters . 2013,第8期

机译：取代的基于黄嘌呤的DPP4抑制剂的综合合成和测试：在药物发现中的应用
2. Practical application of 3-substituted-2,6-difluoropyridines in drug discovery: Facile synthesis of novel protein kinase C theta inhibitors [J] . Katoh Taisuke, Tomata Yoshihide, Setoh Masaki, Bioorganic and Medicinal Chemistry Letters . 2017,第11期

机译：3替代-2,6-二氟吡啶在药物发现中的实际应用：外壳合成新蛋白激酶Cθ抑制剂
3. Synthesis, Activity Testing and Molybdenum(VI) Complexation of Schiff Bases Derived from 2,4,6-Trihydroxybenzaldehyde Investigated as Xanthine Oxidase Inhibitors [J] . Maria Leigh, Carmen E. Castillo, Daniel J. Raines ChemMedChem . 2011,第4期

机译：作为黄嘌呤氧化酶抑制剂的2,4,6-三羟基苯甲醛衍生的席夫碱的合成，活性测试和钼（VI）络合
4. Investigation of substrate and inhibitor behavior towards Beta-Lactamase for application to the development of a LC-MS drug discovery screen. [C] . Mark Zambrowski, Tiffany Palmer, Vladimir Capka American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：β-内酰胺酶对β-内酰胺酶的抑制剂行为的研究，以应用于LC-MS药物发现筛选的发展。
5. Applications of chemical biology in drug discovery and systems biology: Fragment-based design of histone deacetylase inhibitors & A chemical approach to understanding polysaccharide biosynthesis and protein glycosylation. [D] . Woodward, Robert L., Jr. 2010

机译：化学生物学在药物发现和系统生物学中的应用：基于片段的组蛋白脱乙酰基酶抑制剂的设计和一种了解多糖生物合成和蛋白质糖基化的化学方法。
6. Integrated Synthesis and Testing of Substituted XanthineBased DPP4 Inhibitors: Application to Drug Discovery [O] . Werngard Czechtizky, Jüergen Dedio, Bimbisar Desai, 2013

机译：取代黄嘌呤的综合合成与测试基于DPP4的抑制剂：在药物发现中的应用
7. Design, Synthesis, Physical Properties and Indoleamine 2, 3-Dioxygenase 1 Inhibitory Activity of Substituted Indole Derivatives with N-H, N-Methoxymethyl, or N-Mehylthiomethyl Group toward Fragment-Based Drug Discovery [O] . Mitsuhiro Arisawa, Kenta Hayami, Yuichi Kuboki, 2021

机译：设计，合成，物理性质和吲哚胺2,3双加氧酶1与N-H，N-甲氧基，或N- Mehylthiomethyl组朝向片段为基础的药物发现取代吲哚衍生物的抑制活性

Integrated Synthesis and Testing of Substituted Xanthine Based DPP4 Inhibitors: Application to Drug Discovery

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