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Creation and X-ray Structure Analysis of the Tumor Necrosis Factor Receptor-1-selective Mutant of a Tumor Necrosis Factor-α Antagonist

机译：肿瘤坏死因子 - α拮抗剂肿瘤坏死因子受体-1选择性突变体的创造和X射线结构分析

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Hiroko Shibata; Yasuo Yoshioka; Akiko Ohkawa; Kyoko Minowa; Yohei Mukai; Yasuhiro Abe; Madoka Taniai; Tetsuya Nomura; Hiroyuki Kayamuro; Hiromi Nabeshi; Toshiki Sugita; Sunao Imai; Kazuya Nagano; Tomoaki Yoshikawa; Takuya Fujita; Shinsaku Nakagawa; Akira Yamamoto; Tsunetaka Ohta; Takao Hayakawa; Tadanori Mayumi; Peter Vandenabeele; Bharat B. Aggarwal; Teruya Nakamura; Yuriko Yamagata; Shin-ichi Tsunoda; Haruhiko Kamada; Yasuo Tsutsumi;
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1. Microparticles of Human Atherosclerotic Plaques Enhance the Shedding of the Tumor Necrosis Factor- Converting Enzyme/ADAM17 Substrates, Tumor Necrosis Factor and Tumor Necrosis Factor Receptor-1 [J] . Matthias Canault* Aurélie S. Leroyer Franck Peiretti* Guy Lesèche Alain Tedgui Bernadette Bonardo* Marie-Christine Alessi* Chantal M. Boulanger and Gilles Nalbone* American Journal of Pathology . 2007,第5期

机译：人动脉粥样硬化斑块的微粒增强了肿瘤坏死因子转换酶/ ADAM17底物，肿瘤坏死因子和肿瘤坏死因子受体-1的脱落。
2. Microparticles of Human Atherosclerotic Plaques Enhance the Shedding of the Tumor Necrosis Factor-{alpha} Converting Enzyme/ADAM17 Substrates, Tumor Necrosis Factor and Tumor Necrosis Factor Receptor-1. [J] . Canault M, Leroyer AS, Peiretti F, American Journal of Pathology: Official Publication of the American Association of Pathologists . 2007,第5期

机译：人动脉粥样斑块的微粒增强了肿瘤坏死因子-α转化酶/ ADAM17底物，肿瘤坏死因子和肿瘤坏死因子受体1的脱落。
3. Intrathecal ultra-low dose naloxone enhances the antihyperalgesic effects of morphine and attenuates tumor necrosis factor-α and tumor necrosis factor-α receptor 1 expression in the dorsal horn of rats with partial sciatic nerve transection [J] . YangC.-P., CherngC.-H., WuC.-T., Anesthesia and Analgesia: Journal of the International Anesthesia Research Society . 2013,第6期

机译：鞘内超低剂量纳洛酮可增强吗啡的抗痛觉过敏作用，并减弱部分坐骨神经横断大鼠背角中肿瘤坏死因子-α和肿瘤坏死因子-α受体1的表达
4. Tumor Necrosis Factor-α (TNF-α) might play a role in the postprandial metabolism regulation in Duroc×Landrace×Large White growing barrows [C] . H.J.Xu, W.Du, Y.J.LI, Progress in functional amino acids and carbohydrates for animal production . 2009

机译：肿瘤坏死因子-α（TNF-α）可能在Duroc×Landrace×Large White生长的手推车的餐后代谢调节中起作用
5. Evaluation of elastin-like polypeptide to sustain perineural drug delivery and development of a depot-forming tumor necrosis factor antagonist for the treatment of lumbar radiculopathy [D] . Shamji, Mohammed Farid 2008

机译：评估弹性蛋白样多肽维持神经递质给药和开发可用于治疗腰椎神经根病的长效形成肿瘤坏死因子拮抗剂的方法
6. Microparticles of Human Atherosclerotic Plaques Enhance the Shedding of the Tumor Necrosis Factor-α Converting Enzyme/ADAM17 Substrates Tumor Necrosis Factor and Tumor Necrosis Factor Receptor-1 [O] . Matthias Canault, Aurélie S. Leroyer, Franck Peiretti, 2007

机译：人动脉粥样斑块的微粒增强了肿瘤坏死因子-α转化酶/ ADAM17底物肿瘤坏死因子和肿瘤坏死因子受体-1的脱落
7. Association of a Promoter Polymorphism of Tumor Necrosis Factor-α with Subacute Cutaneous Lupus Erythematosus and Distinct Photoregulation of Transcription1,21Werth VP, Sullivan K: Strong association of a promoter polymorphism of tumor necrosis factors α with a photosensitive form of cutaneous lupus erythematosus. Arthr Rheum 42:S105 1999 (abstr.)2Werth VP, Zhang W, Sullivan K: Role of a promoter polymorphism of tumor necrosis factor-α (TNF-α) in a photosensitive form of lupus erythematosus (LE): clinical association and distinct photoregulation of transcription. J Invest Dermatol 114:770 2000 (abstr.) [O] . Werth Victoria P., Zhang Wei, Dortzbach Kathy, 2000

机译：肿瘤坏死因子-α启动子多态性与亚急性皮肤性红斑狼疮和转录的明显光调节相关1,21Werth VP，Sullivan K：肿瘤坏死因子α的启动子多态性与光敏性皮肤性红斑狼疮有很强的联系。 Arthr Rheum 42：S105 1999（摘要）2沃特VP，张W，沙利文K：肿瘤坏死因子-α（TNF-α）启动子多态性在红斑狼疮（LE）的光敏形式中的作用：临床关联和独特之处转录的光调节。 J投资皮肤病杂志114：770 2000（摘要）

Creation and X-ray Structure Analysis of the Tumor Necrosis Factor Receptor-1-selective Mutant of a Tumor Necrosis Factor-α Antagonist

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