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Rationale for Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Combination Therapy with Camptothecins or Temozolomide Based on PARP Trapping versus Catalytic Inhibition

机译：基于PARP诱捕与催化抑制的PARP诱捕，聚（ADP-核糖）聚合酶（PARP）聚合酶（PARP）抑制剂中的基础抑制剂

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Junko Murai; Yiping Zhang; Joel Morris; Jiuping Ji; Shunichi Takeda; James H. Doroshow; Yves Pommier;
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年度 2014
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1. Rationale for poly(ADP-ribose) polymerase (PARP) inhibitors in combination therapy with camptothecins or temozolomide based on PARP trapping versus catalytic inhibition [J] . MuraiJ., ZhangY., MorrisJ., The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2014,第3期

机译：基于喜树碱或替莫唑胺的PARP捕获与催化抑制相结合的聚（ADP-核糖）聚合酶（PARP）抑制剂的原理
2. Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate [J] . Cecilia E. Str?m, Cristina Al-Khalili Szigyarto, Fredrik Johansson, Nucleic acids research . 2011,第8期

机译：聚（ADP-核糖）聚合酶（PARP）不参与碱基切除修复，但PARP抑制作用捕获单链中间体
3. MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination [J] . TentoriL., MuziA., DorioA.S., Cancer chemotherapy and pharmacology. . 2013,第1期

机译：MSH3的表达不影响结肠癌HCT116细胞系对奥沙利铂和聚（ADP-核糖）聚合酶（PARP）抑制剂的单一治疗或联合治疗的敏感性
4. DESIGN AND SYNTHESIS OF NOVEL POLY ADP-RIBOSE POLYMERASE 1(PARP1)INHIBITORS FOR THE TREATMENT OF SOLID TUMORS [C] . J.Priyancy, D.P.Bhumika Conference on Drug Design and Discovery Technologies . 2020

机译：用于治疗实体肿瘤的新型聚ADP-核糖聚合酶1（PARP1）抑制剂的设计与合成
5. Evaluation of selected antioxidants and inhibitors of poly (ADP-ribose) polymerase-1 (PARP-1) as protective agents against mustard toxicity in vitro. [D] . Pino, Maria A. 2010

机译：评价选定的抗氧化剂和聚（ADP-核糖）聚合酶-1（PARP-1）抑制剂作为体外抗芥子油毒性的保护剂。
6. Rationale for Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Combination Therapy with Camptothecins or Temozolomide Based on PARP Trapping versus Catalytic Inhibition [O] . Junko Murai, Yiping Zhang, Joel Morris, -1

机译：基于PARP捕获与催化抑制作用的喜树碱或替莫唑胺联合治疗中的聚（ADP-核糖）聚合酶（PARP）抑制剂的基本原理
7. Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate [O] . Ström, Cecilia E., Johansson, Fredrik, Uhlén, Mathias, 2010

机译：聚（ADP-核糖）聚合酶（PARP）不参与碱基切除修复，但PARP抑制作用会捕获单链中间体

Rationale for Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Combination Therapy with Camptothecins or Temozolomide Based on PARP Trapping versus Catalytic Inhibition

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