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Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia

机译：新型四氢丙杂会衍生物（THPBS）的设计，合成和生物学评价为Proprotein转化酶枯草杆菌素/ kexin型9（PCSK9）调节剂，用于治疗高脂血症

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Chenglin Wu; Cong Xi; Junhua Tong; Jing Zhao; Hualiang Jiang; Jiang Wang; Yiping Wang; Hong Liu;
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1. Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia [J] . Chenglin Wu, Cong Xi, Junhua Tong, Acta Pharmaceutica Sinica B . 2019,第6期

机译：新型四氢丙杂会衍生物（THPBS）的设计，合成和生物学评价为Proprotein转化酶枯草杆菌素/ kexin型9（PCSK9）调节剂，用于治疗高脂血症
2. Design,synthesis,and biological evaluation of novel tetrahydroprotoberberine derivatives(THPBs) as proprotein convertase subtilisin/kexin type 9(PCSK9)modulators for the treatment of hyperlipidemia [J] . Chenglin Wu, Cong Xi, Junhua Tong, 药学学报：英文版 . 2019,第006期

机译：新型四氢原小ber碱衍生物（THPBs）作为原蛋白转化酶枯草杆菌蛋白酶/ kexin 9型（PCSK9）调节剂的设计，合成和生物学评估
3. Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia [J] . Chenglin Wu, Cong Xi, Junhua Tong, 药学学报（英文版） . 2019,第006期

机译：设计，合成和生物学评估新型四氢原小ber碱衍生物（THPBs）作为原蛋白转化酶枯草杆菌蛋白酶/克辛9型调节剂（PCSK9），用于治疗高脂血症
4. Towards Investigating the Role of Proprotein Convertase Subtilisin/Kexin Family (PCSK/7/9) in Cancer by Using Bioinformatics Motif Detection Technique [C] . Umar Draz, Sana Yasin, Shafiq Hussain, International Bhurban Conference on Applied Sciences and Technologies . 2021

机译：通过使用生物信息学主题检测技术来研究Proprotein转化酶枯草杆菌素/ kexin家族（PCSK / 7/9）的作用
5. Evaluation of the Interaction Between Proprotein Convertase Subtilisin/Kexin Type 9 and Sterol Carrier Protein-2 [D] . Ahranjani, Reza. 2017

机译：评价前蛋白转化酶枯草杆菌蛋白酶/ Kexin 9型与甾醇载体蛋白2的相互作用。
6. Design synthesis and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia [O] . Chenglin Wu, Cong Xi, Junhua Tong, 2019

机译：设计合成和生物学评估新颖的四氢原小ine碱衍生物（THPBs）作为原蛋白转化酶枯草杆菌蛋白酶/ kexin 9型（PCSK9）调节剂用于治疗高脂血症
7. Computationally Driven Structure Optimization, Synthesis, and Biological Evaluation of Imidazole-Based Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Inhibitors [O] . -1

机译：基于咪唑基的Proprotein转化酶枯草杆菌蛋白酶/ Kexin 9（PCSK9）抑制剂的计算驱动结构优化，合成和生物学评价

Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia

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