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Resminostat, a histone deacetylase inhibitor, circumvents tolerance to EGFR inhibitors in EGFR-mutated lung cancer cells with BIM deletion polymorphism

机译：Resminostat，一种组蛋白脱乙酰酶抑制剂，将耐受EGFR型肺癌细胞中的耐受性与 BIM缺失多态性

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Sachiko Arai; Shinji Takeuchi; Koji Fukuda; Azusa Tanimoto; Akihiro Nishiyama; Hiroaki Konishi; Akimitsu Takagi; Hiroyuki Takahashi; S. Tiong Ong; Seiji Yano;
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1. The BIM Deletion Polymorphism and its Clinical Implication in Patients with EGFR-Mutant Non-Small-Cell Lung Cancer Treated with EGFR Tyrosine Kinase Inhibitors [J] . Lee Ji Yun, Ku Bo Mi, Lim Sung Hee, Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2015,第6期

机译：EGFR酪氨酸激酶抑制剂治疗EGFR突变型非小细胞肺癌患者的BIM缺失多态性及其临床意义
2. Efficacy of EGFR tyrosine kinase inhibitors in patients with EGFR-mutated non-small cell lung cancer except both exon 19 deletion and exon 21 L858R: A retrospective analysis in Korea [J] . Baek Jin Ho, Sun Jong-Mu, Min Young Joo, Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2015,第2期

机译：EGFR酪氨酸激酶抑制剂对EGFR突变的非小细胞肺癌患者的疗效，第19外显子缺失和第21外显子L858R除外：韩国的一项回顾性分析
3. Dynamic Monitoring and Predictive Value of Circulating Tumor Cells in EGFR-Mutated Advanced Non-Small-Cell Lung Cancer Patients Treated With First-Line EGFR Tyrosine Kinase Inhibitors [J] . Jiang Tao, Zhao Jing, Zhao Chao, Clinical lung cancer . 2019,第2期

机译：用第一线EGFR酪氨酸激酶抑制剂治疗EGFR-突变晚期非小细胞肺癌患者循环肿瘤细胞的动态监测和预测值
4. The Tricyclic Antidepressant Amitriptyline Inhibits D-Cyclin Transactivation and Induces Myeloma Cell Apoptosis by Inhibiting Histone Deacetylases: In Vitro and In Silico Evidence [C] . Xinliang Mao, Depei Wu, Suzanne Trudel, International conference of molecular simulations and applied informatics technologies . 2012

机译：三环抗抑郁药阿米替林通过抑制组蛋白脱乙酰基酶抑制D-cyclin反式激活并诱导骨髓瘤细胞凋亡：体外和计算机证据。
5. Synergistic effects of histone deacetylase and DNA methyltransferase inhibitors on T24 cancer cells [D] . Escobar, Sonia. 2006

机译：组蛋白脱乙酰基酶和DNA甲基转移酶抑制剂对T24癌细胞的协同作用
6. Histone Deacetylase Inhibitors Interrupt HSP90•RASGRP1 and HSP90•CRAF Interactions to Upregulate BIM and Circumvent Drug Resistance in Lymphoma Cells [O] . Husheng Ding, Kevin L. Peterson, Cristina Correia, -1

机译：组蛋白脱乙酰基酶抑制剂可中断HSP90•RASGRP1和HSP90•CRAF相互作用从而上调BIM并避免淋巴瘤细胞产生耐药性
7. The BIM Deletion Polymorphism and its Clinical Implication in Patients with EGFR-Mutant Non–Small-Cell Lung Cancer Treated with EGFR Tyrosine Kinase Inhibitors [O] . Lee Ji Yun, Ku Bo Mi, Lim Sung Hee, 2015

机译：EGFR酪氨酸激酶抑制剂治疗EGFR突变型非小细胞肺癌患者的BIM缺失多态性及其临床意义

Resminostat, a histone deacetylase inhibitor, circumvents tolerance to EGFR inhibitors in EGFR-mutated lung cancer cells with BIM deletion polymorphism

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