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Trend of HIV/AIDS for the last 26 years and predicting achievement of the 90–90-90 HIV prevention targets by 2020 in Ethiopia: a time series analysis

机译:过去26年的艾滋病毒/艾滋病趋势,并在埃塞俄比亚2020年预测90-90-90艾滋病毒预防目标的成就:时间序列分析

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摘要

Abstract Background HIV infection continues to be epidemic of public health importance with a prevalence of 1.1% and incidence of 0.33/1000 population having low-intensity mixed epidemic. Ethiopia has adopted the 90–90-90 by 2020 target but its progress was not yet assessed. Therefore, this study aimed to assess the trend of HIV infection for the last 26 years and to predict the achievements of the 90–90-90 target. Methods We used aggregates of HIV/AIDS indicator data from 1990 to 2016 of UNAIDS data bases. The data were analyzed with excel and STATA. The trend line that best fits the regression was drawn, annual change was estimated and future values of HIV detection rate, coverage of antiretroviral therapy and viral suppression indicators were predicted and compared with the 90–90-90 targets. Result Since 1995, new infection has declined by 81% and since 2002; number of HIV cases has declined by 35.5%. However, after remarkable decline for decades, since 2008 HIV incidence rate began to rise by 10% and number of new infection diagnosed each year increased by 36% among all ages and doubled among adults. ART coverage has increased by 90% among all age and tripled among pregnant women within 6 years. Nationally, 67% of people living with HIV know their status, 88% of them are on treatment and 86% of people on treatment have viral suppression. As a result, AIDS-related death declined by 77 and 79% among all age and children respectively. By 2020, 79% of people living with HIV will know their HIV status, of which 96–99% of HIV infected people will be on ART and more than 86% will have viral suppression. Conclusion After remarkable decline, HIV infection started to increase in the last few years among adults. With the current trend, Ethiopia will achieve the second and third 90% HIV targets, while the first target is not achievable and without achieving this overarching goal control of the epidemic will not be achieved. Therefore due attention is needed to avert the current epidemics and diagnosis of cases.
机译:摘要背景HIV感染仍然是公共卫生意义的流行,流行率为1.1%,发病率为0.33 / 1000人群,具有低强度混合流行病。埃塞俄比亚通过2020年的目标通过了90-90-90,但尚未评估其进度。因此,本研究旨在评估过去26年艾滋病毒感染的趋势,并预测了90-90-90靶的成就。方法采用1990年至2016年艾滋病规划署数据基础的艾滋病毒/艾滋病指标数据的聚集。用Excel和Stata分析数据。最适合回归的趋势线被绘制,预测年度变化和未来的艾滋病毒检测率的价值,抗逆转录病毒治疗和病毒抑制指标的覆盖率,并与90-90-90靶相比。结果自1995年以来,新的感染率下降了81%,自2002年以来;艾滋病毒病例数量下降了35.5%。但是,经过数十年的显着下降,自2008年艾滋病毒艾滋病毒发发率开始增加10%,每年诊断的新感染数量增加36%,成年人增加一倍。艺术覆盖率在6年内,所有年龄的全年和孕妇中增加了90%。全国各地,67%的艾滋病毒患者知道他们的地位,其中88%正在治疗,86%的治疗人员有病毒抑制。因此,所有年龄和儿童的艾滋病相关死亡分别下降了77%和79%。到2020年,79%的艾滋病毒患者将知道他们的艾滋病毒状况,其中96-99%的艾滋病毒感染者将在艺术上,超过86%会有病毒抑制。结论后明显下降,艾滋病病毒感染在成人过去几年开始增加。凭借目前的趋势,埃塞俄比亚将达到第二和第三次90%的艾滋病毒症目标,而第一个目标是无法实现的,而不实现这一流行病的总体目标控制将无法实现。因此,需要关注避免当前的流行病和诊断情况。

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