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SAR650984, A Novel Humanized CD38-Targeting Antibody, Demonstrates Potent Antitumor Activity in Models of Multiple Myeloma and Other CD38+ Hematologic Malignancies

机译：SAR650984是一种新型人源化的CD38靶向抗体，证明了多种骨髓瘤和其他CD38 +血液性恶性肿瘤的模型中有效的抗肿瘤活性

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Jutta Deckert; Marie-Cécile Wetzel; Laura M. Bartle; Anna Skaletskaya; Victor S. Goldmacher; François Vallée; Qing Zhou-Liu; Paul Ferrari; Stéphanie Pouzieux; Charlotte Lahoute; Charles Dumontet; Adriana Plesa; Marielle Chiron; Pascale Lejeune; Thomas Chittenden; Peter U. Park; Véronique Blanc;
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1. SAR650984, A Novel Humanized CD38-Targeting Antibody, Demonstrates Potent Antitumor Activity in Models of Multiple Myeloma and Other CD38 Hematologic Malignancies [J] . Jutta Deckert, Marie-Cecile Wetzel, Laura M. Bartle, Clinical cancer research: an official journal of the American Association for Cancer Research . 2014,第17期

机译：SAR650984，一种新型的人源化CD38靶向抗体，在多发性骨髓瘤和其他CD38血液系统恶性肿瘤模型中显示出强大的抗肿瘤活性
2. Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies. [J] . Horton HM, Bernett MJ, Peipp M, Blood: The Journal of the American Society of Hematology . 2010,第16期

机译：Fc工程化的抗CD40抗体可增强多种效应子功能，并具有针对血液系统恶性肿瘤的有效的体外和体内抗肿瘤活性。
3. Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function [J] . TaiY.-T., HortonH.M., KongS.-Y., Blood: The Journal of the American Society of Hematology . 2012,第9期

机译：Fc工程化的人源化抗HM1.24抗体通过增强的效应子功能对多发性骨髓瘤的体外和体内活性
4. KTN0182A, an Anti-KIT, Pyrrolobenzodiazepine (PBD)-Containing Antibody Drug Conjugate (ADC) Demonstrates Potent Antitumor Activity In Vitro and In Vivo Against a Broad Range of Tumor Types [C] . Sergio Trombetta, Christine Lubeski, Gary C. Kemp, PEGS . 2015

机译：KTN0182A，抗试剂盒，吡咯唑二氮杂己酮（PBD）抗体药物缀合物（ADC）在体外和体内抗抗肿瘤类型的抗肿瘤活性
5. Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function [O] . Yu-Tzu Tai, Holly M. Horton, Sun-Young Kong, -1

机译：Fc工程化的人源化抗HM1.24抗体通过增强的效应子功能对多发性骨髓瘤的体外和体内活性
6. Antitumor activity of humanized monoclonal antibody against HM1.24 antigen in human myeloma xenograft models [O] . Shigeto Kawai, Yasushi Yoshimura, Shin-ichiro Iida, 2006

机译：人骨髓瘤异种移植模型中抗HM1.24抗原的人源化单克隆抗体的抗肿瘤活性

SAR650984, A Novel Humanized CD38-Targeting Antibody, Demonstrates Potent Antitumor Activity in Models of Multiple Myeloma and Other CD38+ Hematologic Malignancies

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