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Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure

机译：两性离子羟基氨基甲酰氨基胺烷基胺的药理，药代动力学和组织置位作为有机磷暴露的反应解毒剂

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Rakesh K. Sit; Zrinka Kovarik; Nikolina Maček Hrvat; Suzana Žunec; Carol Green; Valery V. Fokin; K. Barry Sharpless; Zoran Radić; Palmer Taylor;
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1. Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure [J] . Sit Rakesh K., Kovarik Zrinka, Hrvat Nikolina Macek, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2018,第2期

机译：两性离子羟基氨基甲酰氨基胺烷基胺的药理，药代动力学和组织置位作为有机磷暴露的反应解毒剂
2. Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure [J] . Taylor Palmer, Yan-Jye Shyong, Momper Jeremiah, Chemico-biological interactions . 2019,第期

机译：可电离的两性离子肟的评估为有机磷暴露的重塑抗体试剂
3. Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of Stage 2 Human African Trypanosomiasis [J] . WringS., GaukelE., NareB., Parasitology . 2014,第1期

机译：药物动力学和药效学利用未受限制的靶组织暴露作为基于方位的基本原理来优化苯并恶硼酸铅在治疗2期人类非洲锥虫病中的应用
4. Paraoxonase 1 (PON1) Status in Risk Assessment for Organophosphate Exposure and Pharmacokinetics [C] . Clement E. Furlong, Rebecca J. Richter, Lucio G. Costa, ACS national meeting . 2012

机译：对氧磷酶1（PON1）在有机磷暴露和药代动力学风险评估中的地位
5. Integration of preclinical and clinical data with pharmacokinetic modeling and simulations to characterize the disposition of orally-active antiparasitic prodrugs and metabolites: Prediction of the dose-exposure relationship in humans. [D] . Yan, Zhixia. 2011

机译：临床前和临床数据与药代动力学建模和模拟的集成，以表征口服活性抗寄生虫前药和代谢物的分布：预测人类的剂量-暴露关系。
6. Pharmacology Pharmacokinetics and Tissue Disposition ofZwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes forOrganophosphate Exposure [O] . Rakesh K. Sit, Zrinka Kovarik, Nikolina Maček Hrvat, -1

机译：的药理学药代动力学和组织处置两性离子羟基氨基乙酰胺烷基胺作为活化解毒剂有机磷暴露
7. Pharmacokinetics of a Mono-pyridinium-mono-aldoxime (K-347), a Potential Antidote in Organophosphate Poisoning [O] . Huba Kalász, Gellért Karvaly, Ferenc Szimrók, 2020

机译：单吡啶-Mono-aldoxime（K-347）的药代动力学，有机磷中毒的潜在解毒剂
8. Comparative Kinetics and Distribution to Target Tissues of Organophosphates Using Physiologically - Based Pharmacokinetic Modeling; Master's thesis [R] . Vermillion, R. E. 2008

机译：使用基于生理学的药代动力学模型比较有机磷酸盐靶组织的动力学和分布;硕士论文

Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure

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