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Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-dependent DNA Double-strand Breaks Induced by Mammalian DNA Topoisomerase I Cleavage Complexes

机译：作用的依赖于复合依赖性DNA双链断裂致响应于哺乳动物DNA拓扑异构酶裂解复合物的复合复合物诱导的复合物诱导的复合依赖性DNA双链断裂的组蛋白H2AX和MRE11，RAD50和NBS1的磷酸化

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Takahisa Furuta; Haruyuki Takemura; Zhi-Yong Liao; Gregory J. Aune; Christophe Redon; Olga A. Sedelnikova; Duane R. Pilch; Emmy P. Rogakou; Arkady Celeste; Hua Tang Chen; Andre Nussenzweig; Mirit I. Aladjem; William M. Bonner; Yves Pommier;
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1. Breast cancer risk is associated with the genes encoding the DNA double-strand break repair Mre11/Rad50/Nbs1 complex. [J] . Hsu HM, Wang HC, Chen ST, Cancer epidemiology, biomarkers and prevention: A publication of the American Association for Cancer Research . 2007,第10期

机译：乳腺癌的风险与编码DNA双链断裂修复Mre11 / Rad50 / Nbs1复合体的基因有关。
2. The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM. [J] . Paull TT, Lee JH Cell cycle . 2005,第6期

机译：Mre11 / Rad50 / Nbs1复合物及其作为ATM的DNA双链断裂传感器的作用。
3. Most hydrogen peroxide-induced histone H2AX phosphorylation is mediated by ATR and is not dependent on DNA double-strand breaks [J] . KatsubeT., MoriM., TsujiH., The Journal of Biochemistry . 2014,第2期

机译：大多数过氧化氢诱导的组蛋白H2AX磷酸化是由ATR介导的，并且不依赖于DNA双链断裂
4. Development of a Quantitative SRM Assay for Histone H2AX Ser139 Phosphorylation, a Key Regulator of the DNA Damage Response (DDR) [C] . V Lunyak, A Prakash, M Athanas, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：组蛋白H2AX Ser139磷酸化的定量SRM测定，DNA损伤响应的关键调节器（DDR）
5. The role of Rad50, Mre11 and Nbs1 complex in DNA double strand break repair. [D] . Tabah, Azah A. 2006

机译：Rad50，Mre11和Nbs1复合体在DNA双链断裂修复中的作用。
6. MRE11–RAD50–NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair [O] . Céline Roques, Yan Coulombe, Mathieu Delannoy, 2009

机译：MRE11–RAD50–NBS1是DNA双链断裂修复过程中FANCD2稳定性和功能的关键调节剂
7. MRE11–RAD50–NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair [O] . Roques, Céline, Coulombe, Yan, Delannoy, Mathieu, 2009

机译：MRE11–RAD50–NBS1是DNA双链断裂修复过程中FANCD2稳定性和功能的关键调节剂

Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-dependent DNA Double-strand Breaks Induced by Mammalian DNA Topoisomerase I Cleavage Complexes

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