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Intratumoral Distribution and pH-Dependent Drug Release of High Molecular Weight HPMA Copolymer Drug Conjugates Strongly Depend on Specific Tumor Substructure and Microenvironment

机译：高分子量HPMA共聚物缀合物的肿瘤内分布和pH依赖性药物释放强烈地取决于特异性肿瘤亚结构和微环境

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Anne-Kathrin Noack; Henrike Lucas; Petr Chytil; Tomáš Etrych; Karsten Mäder; Thomas Mueller;
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1. HPMA Copolymer–Drug Conjugates with Controlled Tumor‐Specific Drug Release [J] . Chytil Petr, Koziolová Eva, Etrych Tomá?, Macromolecular bioscience . 2018,第1期

机译：HPMA共聚物 - 药物缀合物，具有受控肿瘤特异性药物释放
2. Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release II: Impact of release rate on biodistribution [J] . Chytil P., Hoffmann S., Schindler L., Journal of Controlled Release: Official Journal of the Controlled Release Society . 2013,第2期

机译：pH敏感药物释放用于被动靶向肿瘤的双重荧光HPMA共聚物II：释放速率对生物分布的影响
3. Dual Fluorescent HPMA Copolymers for Passive Tumor Targeting with pH-Sensitive Drug Release: Synthesis and Characterization of Distribution and Tumor Accumulation in Mice by Noninvasive Multispectral Optical Imaging [J] . Stefan Hoffmann, Lucie Vystrcilova, Karel Ulbrich Biomacromolecules . 2012,第3期

机译：双荧光HPMA共聚物，用于靶向pH敏感药物释放的被动肿瘤：无创多光谱光学成像在小鼠体内的分布和肿瘤蓄积的合成和表征
4. DESIGN OF HPMA COPOLYMER-DRUG CONJUGATES FOR COLON-SPECIFIC DELIVERY OF 9-AMINOCAMPTOTHECIN [C] . S. Sakuma, Z. -R. Lu, P. Kopeckova, International symposium on controlled release of bioactive materials;Consumer diversified products conference . 2001

机译：用于9-氨基喜树碱结肠特异性转运的HPMA共聚物-药物共轭物的设计
5. The Use of HPMA Copolymer Conjugates for the Intracellular Targeting of Anticancer Drugs [D] . Callahan, Jon Doyle. 2017

机译：HPMA共聚物结合物用于抗癌药物的细胞内靶向
6. Effect of Intratumoral Injection on the Biodistribution and the Therapeutic Potential of HPMA Copolymer-Based Drug Delivery Systems [O] . Twan Lammers, Peter Peschke, Rainer Kühnlein, 2006

机译：瘤内注射对HPMA共聚物基药物传递系统的生物分布和治疗潜力的影响
7. Effect of Intratumoral Injection on the Biodistribution, the Therapeutic Potential of HPMA Copolymer-Based Drug Delivery Systems [O] . Twan Lammers, Peter Peschke, Rainer Kühnlein, 2006

机译：肿瘤内注射对Hpma共聚物基药物传递系统的生物分布，治疗潜力的影响

Intratumoral Distribution and pH-Dependent Drug Release of High Molecular Weight HPMA Copolymer Drug Conjugates Strongly Depend on Specific Tumor Substructure and Microenvironment

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