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The Uptake Inhibitors Cocaine and Benztropine Differentially Alter the Conformation of the Human Dopamine Transporter

机译：摄取抑制剂可卡因和苯并掺杂差异地改变了人多巴胺转运蛋白的构象

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Maarten E.A. Reith; Janet L. Berfield; Lijuan C. Wang; Jasmine V. Ferrer; Jonathan A. Javitch;
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年度 2001
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1. Recognition of Benztropine by the Dopamine Transporter (DAT) Differs from That of the Classical Dopamine Uptake Inhibitors Cocaine,Methylphenidate,and Mazindol as a Function of a DAT Transmembrane 1 Aspartic Acid Residue [J] . Okechukwu T.Ukairo, Corry D.Bondi, Amy Hauck Newman, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2005,第2期

机译：多巴胺转运蛋白（DAT）对苯卓平的识别不同于经典的多巴胺摄取抑制剂可卡因，哌醋甲酯和Mazindol，这取决于DAT跨膜1天冬氨酸残基的功能。
2. Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties. [J] . Schmitt KC, Zhen J, Kharkar P, Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2008,第4期

机译：可卡因，苄索品碱和GBR12909样化合物与野生型和突变型人多巴胺转运蛋白的相互作用：分子特征可区别地确定拮抗剂的结合特性。
3. Synthesis and Pharmacology of 6-Substituted Benztropines:Discovery of Novel Dopamine Uptake Inhibitors Possessing Low Binding Affinity to the Dopamine Transporter [J] . Daniele Simoni, Marcello Rossi, Valeric Bertolasi, Journal of Medicinal Chemistry . 2005,第9期

机译：6取代的苯丙酮的合成与药理作用：发现对多巴胺转运蛋白具有低结合亲和力的新型多巴胺摄取抑制剂。
4. EVALUATION OF THE TRANSCELLULAR TRANSPORT OF CERIVASTATIN ACROSS A DOUBLE-TRANSFECTED MDCKII CELL MONOLAYER EXPRESSING HUMAN OATP2 (UPTAKE TRANSPORTER) AND MRP2 (EFFLUX TRANSPORTER): A NEW SCREENING SYSTEM FOR TRANSEPITHELIAL TRANSPORT OF DRUGS [C] . S. Matsushima, K. Maeda, Y. Shitara, Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

机译：跨人表达人OATP2（摄取转运蛋白）和MRP2（外排转运蛋白）的双通道MDCKII细胞单层转运中西立伐他汀跨细胞转运的评估：药物经皮转运的新筛选系统
5. Dopamine uptake inhibition potency fluctuations of cocaine at the dopamine transporter. [D] . Ramanujapuram, Suneetha. 2006

机译：多巴胺转运蛋白上可卡因的多巴胺吸收抑制效能波动。
6. INTERACTION OF COCAINE- BENZTROPINE- AND GBR12909-LIKE COMPOUNDS WITH WILDTYPE AND MUTANT HUMAN DOPAMINE TRANSPORTERS: MOLECULAR FEATURES THAT DIFFERENTIALLY DETERMINE ANTAGONIST BINDING PROPERTIES [O] . Kyle C. Schmitt, Juan Zhen, Prashant Kharkar, -1

机译：类似于可卡因苯并三嗪和GBR12909的化合物与野生型和突变型人多巴胺转运蛋白的相互作用：分别确定拮抗剂结合特性的分子特征
7. Synthesis and Pharmacology of 6-Substituted Benztropines: Discovery of Novel Dopamine Uptake Inhibitors Possessing Low Binding Affinity to the Dopamine Transporter [O] . Daniele Simoni, Marcello Rossi, Valerio Bertolasi, 2004

机译：6-取代苯并噻嗪的合成和药理学：发现新的多巴胺摄取抑制剂对多巴胺转运蛋白具有低结合亲和力
8. Investigation of the Stoichiometry of Na+ Cotransport with Dopamine in Rat and Human Dopamine Transporters Expressed in Human Embryonic Kidney Cells [R] . Schumacher, P. D. 2001

机译：多巴胺对人胚肾细胞表达大鼠和人多巴胺转运体Na +协同转运的化学计量学研究

The Uptake Inhibitors Cocaine and Benztropine Differentially Alter the Conformation of the Human Dopamine Transporter

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