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Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT

机译：嘧啶-4,6-二胺衍生物作为FLT3对C-kit选择性的II型II型抑制剂的合理设计，合成及生物学评价

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Jaideep B. Bharate; Nicholas McConnell; Gunaganti Naresh; Lingtian Zhang; Naga Rajiv Lakkaniga; Lucky Ding; Neil P. Shah; Brendan Frett; Hong-yu Li;
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1. Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT [J] . Jaideep B. Bharate, Nicholas McConnell, Gunaganti Naresh, Scientific reports. . 2018,第1期

机译：嘧啶-4,6-二胺衍生物作为FLT3对C-kit选择性的II型II型抑制剂的合理设计，合成及生物学评价
2. Design, synthesis and pharmacological evaluation of N4,N6-disubstituted pyrimidine-4,6-diamine derivatives as potent EGFR inhibitors in non-small cell lung cancer [J] . Zhang Yuan, Lv Handeng, Luo Lu, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2018,第期

机译：N4，N6-二取代的嘧啶-4,6-二胺衍生物的设计，合成和药理学评价为非小细胞肺癌中有效的EGFR抑制剂
3. Structure-based design and synthesis of pyrimidine-4,6-diamine derivatives as Janus kinase 3 inhibitors [J] . Yu Ru-Nan, Chen Cheng-Juan, Shu Lei, Bioorganic and medicinal chemistry . 2019,第8期

机译：基于结构的设计和合成嘧啶-4,6-二胺衍生物，如Janus激酶3抑制剂
4. Design, Synthesis, and Pharmacological Evaluation of Novel Tasiamide B Derivatives: Selective Inhibitors of BACE1 [C] . Jian Liu, SimingYang, Wei Zhang, Chinese International Peptide Symposium . 2013

机译：新型三胺B衍生物的设计，合成和药理评价：BACE1的选择性抑制剂
5. Structure-Based Drug Design in Medicinal Chemistry: I. Development of Translesion Synthesis Inhibitors II. Synthesis and Biological Evaluation of Sulfonyl Piperazine Derivatives for LpxH Inhibition [D] . Lee, Minhee 2017

机译：药物化学中基于结构的药物设计：I.跨病变合成抑制剂的开发II。磺酰哌嗪衍生物对LpxH的抑制作用及其合成及生物学评价
6. Rational Design Synthesis and Biological Evaluation of Pyrimidine-46-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT [O] . Jaideep B. Bharate, Nicholas McConnell, Gunaganti Naresh, -1

机译：嘧啶-46-二胺衍生物作为对c-KIT选择性的FLT3 II型抑制剂的合理设计合成和生物学评估
7. Design, synthesis, biological evaluation and molecular docking of 1,7-dibenzyl substituted theophylline derivatives as novel BRD4-BD1 selective inhibitors [O] . Ying-Jie Chang, Jin-Ge Zhang, Shuang-Shuang Yang, 2021

机译：1,7-二苄基取代的茶碱衍生物作为新型BRD4-BD1选择性抑制剂的设计，合成，生物学评价和分子对接

Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT

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