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Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties

机译：引入免疫球蛋白恒定结构域的结构环中的抗原结合位点：Fc片段与工程化HER2 / Neu结合位点和抗体特性

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G. Wozniak-Knopp; S. Bartl; A. Bauer; M. Mostageer; M. Woisetschläger; B. Antes; K. Ettl; M. Kainer; G. Weberhofer; S. Wiederkum; G. Himmler; G.C. Mudde; F. Rüker;
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年度 2010
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1. Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2eu-binding sites and antibody properties. [J] . Wozniak Knopp G, Bartl S, Bauer A, Protein engineering design & selection: PEDS . 2010,第3a4期

机译：在免疫球蛋白恒定域的结构环中引入抗原结合位点：具有工程化的HER2 / neu结合位点和抗体特性的Fc片段。
2. Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2eu-bindingn sites and antibody properties [J] . F. Rüker Protein Engineering, Design and Selection . 2010,第4期

机译：在免疫球蛋白恒定域的结构环中引入抗原结合位点：具有工程化的HER2 / neu结合位点和抗体特性的Fc片段
3. In vivo and in vitro activity of an immunoglobulin Fc fragment (Fcab) with engineered Her-2eu binding sites [J] . Max Woisetschlager, Bernhardt Antes, Radha Borrowdale Biotechnology Journal: Healthcare,Nutrition,Technology . 2014,第6期

机译：具有工程Her-2 / neu结合位点的免疫球蛋白Fc片段（Fcab）的体内和体外活性
4. Site-Specific Immobilization of Recombinant Antibody Fragments for Biosensing [C] . Yoichi Kumada AIChE annual meeting . 2010

机译：用于生物传感的重组抗体片段的位点特异性固定
5. A novel approach to control and regulate the classical complement pathway: Highly specific inhibition of C1q globular head binding to human IgG using an engineered single chain antibody variable fragment; recruiting C1q to HER2 /neu positive cells using truncated bispecific antibodies [D] . Hwang, Hee Young 2007

机译：一种控制和调节经典补体途径的新方法：使用工程化的单链抗体可变片段高度特异性地抑制C1q球头与人IgG的结合；使用截短的双特异性抗体将C1q募集到HER2 / neu阳性细胞
6. Immunoglobulin-binding Sites of Human FcαRI (CD89) and Bovine Fcγ2R Are Located in their Membrane-distal Extracellular Domains [O] . H. Craig Morton, Ger van Zandbergen, Cees van Kooten, 1999

机译：人FcαRI（CD89）和牛Fcγ2R的免疫球蛋白结合位点位于其膜远端细胞外域。
7. Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site [O] . Sean W. Fanning, Richard Walter, James R. Horn 2014

机译：工程双特异性抗体的结构基础：构象多样性导致高变环金属结合位点

Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties

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