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Preparation of Parenteral in situ Gel Formulation Based on smart PLGA polymer: Concepts to Decrease Initial Drug Burst and extend drug release

机译：基于智能PLGA聚合物的肠胃外肠外凝胶制剂的制备：减少初始药物爆发的概念并延伸药物释放

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Tarek Ahmed; Zahid Hussain;
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1. LIPOPHILIC AND HYDROPHILIC DRUG LOADED PLA/PLGA IN SITU IMPLANTS: STUDIES ON THERMAL BEHAVIOR OF DRUG & POLYMER AND OBSERVATION OF PARAMETERS INFLUENCING DRUG BURST RELEASE WITH CORRESPONDING EFFECTS ON LOADING EFFICIENCY & MORPHOLOGY OF IMPLANTS [J] . SWARNALI ISLAM International Journal of Pharmacy and Pharmaceutical Sciences . 2011,第Suppla3期

机译：脂质和疏水药物在原位植入的PLA / PLGA：药物和聚合物的热行为以及影响药物爆发的参数的观察以及相应的效应，以改善植入物的加载效率和形态
2. A Novel Preparation Method for Octreotide Acetate-Loaded PLGA Microspheres with a High Drug-Loading Capacity and a Low Initial Burst Release, and Its Studies on Relations between In Vitro and In Vivo Release [J] . BIN CHEN, BING HAN, LIPING SONG Advances in Polymer Technology . 2013,第3期

机译：高载药量和低初始爆发释放度的醋酸奥曲肽载PLGA微球的制备方法及其体外与体内释放关系的研究
3. Influence of end groups on in vitro release and biological activity of lysozyme from a phase-sensitive smart polymer-based in situ gel forming controlled release drug delivery system. [J] . Chhabra S, Sachdeva V, Singh S International Journal of Pharmaceutics . 2007,第1a2期

机译：端基对基于相敏智能聚合物的原位凝胶形成控释药物递送系统的溶菌酶的体外释放和生物学活性的影响。
4. Prolonged Drug Release from a Novel Gel Formulation Composed of Drug Containing Catanionic Vesicles and Oppositely Charged Hydrophobically Modified Polymer, Intended for e.g. Transdermal Applications [C] . Annual meeting exposition of the Controlled Release Society . 2009

机译：从含有含有含有的含有薄叠囊泡的药物和相反的疏水改性聚合物组成的新型凝胶制剂的延长药物释放，所述凝胶制剂包括例如用于例如E.G的药物。透皮应用
5. Controlling drug delivery for the application of extended or sustained-release drug products for parenteral administration. [D] . O'Neil, Jacklyn. 2010

机译：控制药物的递送，以用于肠胃外给药的缓释或缓释药物产品的应用。
6. Polymer Pro-Drug Nanoparticles for Sustained Release of Cytotoxic Drugs Evaluated in Patient-Derived Glioblastoma Cell Lines and In Situ Gelling Formulations [O] . Catherine E. Vasey, Robert J. Cavanagh, Vincenzo Taresco, 2021

机译：用于在患者衍生的胶质母细胞系细胞系和原位胶凝配方中评估的细胞毒性药物的持续释放的聚合物促药物纳米粒子
7. Bioerodable PLGA-Based Microparticles for Producing Sustained-Release Drug Formulations and Strategies for Improving Drug Loading [O] . Felicity Y. Han, Kristofer J. Thurecht, Andrew K. Whittaker, 2016

机译：用于生产缓释药物制剂的可生物降解的pLGa基微粒和改善药物负载的策略

Preparation of Parenteral in situ Gel Formulation Based on smart PLGA polymer: Concepts to Decrease Initial Drug Burst and extend drug release

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