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Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial

机译：四因素凝血酶浓缩浓缩物与血浆快速维生素K拮抗剂逆转，患者需要紧急外科或侵袭性干预：第3B期，开放标签，非劣等，随机试验

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Joshua N Goldstein; Majed A Refaai; Truman J Milling; Brandon Lewis; Robert Goldberg-Alberts; Bruce A Hug; Ravi Sarode;
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年度 2015
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1. Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial [J] . Goldstein Joshua N., Refaai Majed A., Milling Truman J. Jr., The Lancet . 2015,第9982期

机译：四因子凝血酶原复合物浓缩物与血浆相比，可在需要紧急外科或侵入性干预的患者中快速逆转维生素K拮抗剂：3b期，开放标签，非劣效性，随机试验
2. Efficacy and safety of a 4-factor prothrombin complex concentrate for rapid vitamin K antagonist reversal in Japanese patients presenting with major bleeding or requiring urgent surgical or invasive procedures: a prospective, open-label, single-arm phase 3b study [J] . Shigeki Kushimoto, Toshio Fukuoka, Akio Kimura, International journal of hematology . 2017,第6期

机译：4因素凝血酶浓缩物的疗效和安全性在日本患者中快速维生素K拮抗剂逆转的效果和安全性，或者需要紧急外科手术或侵入手术：前瞻性，开放标签，单臂第3B研究
3. Four-Factor Prothrombin Complex Concentrate Versus Plasma for Urgent Vitamin K Antagonist Reversal New Evidence [J] . Ravi Sarode Clinics in laboratory medicine . 2014,第3期

机译：四因子凝血酶原复合物对血浆与紧急维生素K拮抗剂逆转的新证据
4. Reversal of Warfarin-Associated Coagulopathy: Prothrombin Complex Concentrates Versus Fresh Frozen Plasma in Elderly Patients Presenting with Intracranial Hemorrhage [D] . Lumas, Shunella Grace. 2020

机译：逆转华法林相关凝血病：凝血酶原浓缩物与颅内出血患者的老年患者新鲜冷冻血浆
5. Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b open-label non-inferiority randomised trial [O] . Joshua N Goldstein, Majed A Refaai, Truman J Milling Jr, -1

机译：四因子凝血酶原复合物浓缩物与血浆相比可在需要紧急外科或侵入性干预的患者中快速逆转维生素K拮抗剂：3b期开放标签非劣效性随机试验
6. Prothrombin complex concentrate in surgical patients: retrospective evaluation of vitamin K antagonist reversal and treatment of severe bleeding [O] . Kerstin S Schick, Jan M Fertmann, Karl-Walter Jauch, 2009

机译：凝血酶原复合物在外科手术患者中的应用：维生素K拮抗剂逆转和严重出血治疗的回顾性评估

Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial

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