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A Computational Toxicology Approach to Screen the Hepatotoxic Ingredients in Traditional Chinese Medicines: Polygonum multiflorum Thunb as a Case Study

机译：一种筛选中药中肝毒性成分的计算毒理学方法：Polygonum Multiflorum Thunb作为案例研究

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Shuaibing He; Xuelian Zhang; Shan Lu; Ting Zhu; Guibo Sun; Xiaobo Sun;
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1. UHPLC-QQQ-MS/MS assay for the quantification of dianthrones as potential toxic markers of Polygonum multiflorum Thunb: applications for the standardization of traditional Chinese medicines (TCMs) with endogenous toxicity [J] . Yang Jian-Bo, Song Yun-Fei, Liu Yue, Chinese Medicine . 2021,第1期

机译：UHPLC-QQQ-MS / MS测定用于定量促性蒽醌的潜在有毒标志物：具有内源性毒性的中药（TCMS）标准化的应用
2. Identification of new dianthrone glycosides from Polygonum multiflorum Thunb. using high-performance liquid chromatography coupled with LTQ-Orbitrap mass spectrometry detection: a strategy for the rapid detection of new low abundant metabolites from traditional Chinese medicines [J] . Jing Zhang, Zhihai Huang, Xiaohui Qiu Analytical methods . 2012,第6期

机译：从何首乌中提取新的二蒽酮苷。高效液相色谱法结合LTQ-Orbitrap质谱检测技术：快速检测中药中新的低丰度代谢物的策略
3. Insights into the molecular mechanisms of Polygonum multiflorum Thunb-induced liver injury:a computational systems toxicology approach [J] . Yin-yin WANG, Yun TANG, Jie LI, 中国药理学报：英文版 . 2017,第005期

机译：何首乌诱导的肝损伤分子机制的见解：一种计算系统毒理学方法
4. Prediction of hepatotoxicity of traditional Chinese medicine compounds by support vector machine approach [C] . Jiang Ludi, He Yusu, Zhang Yanling International Conference on Systems Biology . 2014

机译：支持向量机方法预测中药化合物的肝毒性
5. Screening of IRE1α Ribonuclease Inhibitors from Traditional Chinese Medicine and Underlying Anticancer Mechanisms Study [D] . Xie, Jing. 2021

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6. A Computational Toxicology Approach to Screen the Hepatotoxic Ingredients in Traditional Chinese Medicines: Polygonum multiflorum Thunb as a Case Study [O] . Shuaibing He, Xuelian Zhang, Shan Lu, 2019

机译：一种计算毒理学方法筛选中药肝毒性成分的研究：何首乌为例
7. Insights into the molecular mechanisms of Polygonum multiflorum Thunb-induced liver injury: a computational systems toxicology approach [O] . Yin-yin Wang, Jie Li, Zeng-rui Wu, 2017

机译：洞察兼达百叶植物诱导肝损伤的分子机制：毒理学方法的计算系统

A Computational Toxicology Approach to Screen the Hepatotoxic Ingredients in Traditional Chinese Medicines: Polygonum multiflorum Thunb as a Case Study

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