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Application of physiologically-based pharmacokinetic modeling to explore the role of kidney transporters in renal reabsorption of perfluorooctanoic acid in the rat

机译：基于生理学的药代动力学建模在大鼠全氟辛酸肾脏重吸收中的应用探讨肾脏转运蛋白的应用

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Rachel Rogers Worley; Jeffrey Fisher;
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1. Application of physiologically-based pharmacokinetic modeling to explore the role of kidney transporters in renal reabsorption of perfluorooctanoic acid in the rat [J] . Worley Rachel Rogers, Fisher Jeffrey Toxicology and Applied Pharmacology . 2015,第3期

机译：基于生理学的药代动力学模型在探索肾脏转运蛋白在大鼠全氟辛酸肾脏重吸收中的作用
2. Semi-mechanistic kidney model incorporating physiologically-relevant fluid reabsorption and transporter-mediated renal reabsorption: pharmacokinetics of gamma-hydroxybutyric acid and l-lactate in rats [J] . Dave Rutwij A., Morris Marilyn E. Journal of pharmacokinetics and pharmacodynamics . 2015,第5期

机译：结合生理相关的液体重吸收和转运蛋白介导的肾脏重吸收的半机械肾脏模型：γ-羟基丁酸和l-乳酸在大鼠中的药代动力学
3. PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELS WITH INTEGRATED RENAL TRANSPORTER ONTOGENY PREDICT SYSTEMIC EXPOSURE TO TAZOBACTAM, OSELTAMIVIR, AND OSELTAMIVIR CARBOXYLATE IN CHILDREN. [J] . Cheung K., Zhang L., Huang S. M., Clinical Pharmacology and Therapeutics . 2019,第Suppla1期

机译：基于生理学的药代动力学模型，肾脏转运蛋白组织发生，预测儿童塔唑酰胺，奥司他米和Oseltamivir羧酸盐的全身接触。
4. A Physiologically-Based Pharmacokinetic Model of Methotrexate Incorporating Hepatic Excretion via Multidrug-Resistance-Associated Protein 2 (Mrp2) in Mice, Rats, Dogs, and Humans [C] . Manupat Lohitnavy, Yasong Lu, Ornrat Lohitnavy, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2017

机译：通过小鼠，大鼠，狗和人类，通过多药抗性相关蛋白2（MRP2）掺入肝细胞排泄的生理学上的药代动力学模型
5. Quantitative Structure Pharmacokinetic Relationships (QSPKR) and Mechanistic Models for Transporter-Mediated Renal Drug Disposition. [D] . Dave, Rutwij A. 2016

机译：转运蛋白介导的肾脏药物处置的定量结构药代动力学关系（QSPKR）和机理模型。
6. Application of Physiologically-Based Pharmacokinetic Modeling to Explore the Role of Kidney Transporters in Renal Reabsorption of Perfluorooctanoic Acid in the Rat [O] . Rachel Rogers Worley, Jeffrey Fisher -1

机译：生理基础药代动力学模型在探索肾脏转运蛋白在大鼠全氟辛酸肾脏重吸收中的作用的应用
7. Delineating the role of various factors in renal disposition of digoxin through application of physiologically-based kidney model to renal impairment populations [O] . Scotcher, Daniel, Jones, Christopher, Galetin, Aleksandra, 2017

机译：通过将生理学肾模型应用于肾损伤人群，阐明各种因素在地高辛肾脏处置中的作用
8. Quantitative Evaluation of Dichloroacetic Acid Kinetics in Human -- A Physiologically-Based Pharmacokinetic Modeling Investigation [R] . Li, T., Schultz, I., Keys, D. A., 2008

机译：人体内二氯乙酸动力学的定量评价 - 基于生理学的药代动力学模型研究

Application of physiologically-based pharmacokinetic modeling to explore the role of kidney transporters in renal reabsorption of perfluorooctanoic acid in the rat

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