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Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes suggests that hPXR is less sensitive than mouse PXR to nonylphenol treatment

机译：壬基酚介导的CYP诱导是PXR依赖性：使用人源化小鼠和人肝细胞的使用表明，HPXR比小鼠PXR对壬基酚处理敏感

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Linda C. Mota; Christina Barfield; Juan P. Hernandez; William S. Baldwin;
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年度 2011
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1. Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes suggests that hPXR is less sensitive than mouse PXR to nonylphenol treatment. [J] . Mota LC, Barfield C, Hernandez JP, Toxicology and Applied Pharmacology . 2011,第3期

机译：壬基酚介导的CYP诱导是PXR依赖性的：人源化小鼠和人类肝细胞的使用表明hPXR对小鼠的壬基酚治疗的敏感性低于小鼠PXR。
2. Rifampin-Mediated Induction of Tamoxifen Metabolism in a Humanized PXR-CAR-CYP3A4/3A7-CYP2D6 Mouse Model [J] . Chang Jae H., Chen John, Liu Liling, Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2016,第11期

机译：利福平介导的人源化PXR-CAR-CYP3A4 / 3A7-CYP2D6小鼠模型中他莫昔芬代谢的诱导
3. The effect of rifampin-mediated induction of tamoxifen metabolism in humanized PXR-CAR-CYP3A4/3A7-CYP2D6 mouse model [J] . Chang Jae H., Chen John, Messick Kirsten, Drug Metabolism Reviews . 2016,第1a4期

机译：利福平介导的他莫昔芬代谢在人源化PXR-CAR-CYP3A4 / 3A7-CYP2D6小鼠模型中的作用
4. Metabolites of Thalidomide Using the Humanized CYP3A Transchromosomic Mouse Liver Microsome, Detected by LC-MS/MS system [C] . Shin-ichiro Nitta, Yasuko Tsukazaki, Naoto Senda, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：使用LC-MS / MS系统检测的人源化CYP3A转斜圆锥组种小鼠肝微小肝微小羟基核素小鼠肝微粒的代谢物
5. 4-nonylphenol attenuates dexamethasone induction of CYP2B and CYP3A in FVB/NJ mice. [D] . Hernandez, Juan. 2004

机译：4-壬基苯酚减弱FVB / NJ小鼠中地塞米松对CYP2B和CYP3A的诱导作用。
6. Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes suggests that hPXR is less sensitive than mouse PXR to nonylphenol treatment [O] . Linda C Mota, Christina Barfield, Juan P Hernandez, -1

机译：壬基酚介导的CYP诱导是PXR依赖性：使用人源化小鼠和人肝细胞的使用表明HPXR比小鼠PXR对壬基酚处理敏感
7. CYP1A1 and CYP1A2 expression: Comparing ‘humanized’ mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell lines [O] . Shigeyuki Uno, Kaori Endo, Yuji Ishida, 2009

机译：CYP1A1和CYP1A2表达：比较“人源化”小鼠线和野生型小鼠;比较人和小鼠肝癌衍生的细胞系

Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes suggests that hPXR is less sensitive than mouse PXR to nonylphenol treatment

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