IntroductionThe aim was to evaluate the association between secondhand smoke(SHS) exposure and abnormal cervical cytology among Chinese adult women.MethodsA one-to-one matched case-control study was conducted with outpatientsof the First Hospital of Jilin University between October 2013 to September2016. In all, 228 cytologic confirmed new cases of abnormal cervical cytologyand the equivalent number of age and ethnic matched controls were interviewedabout SHS exposure and related factors.ResultsAlthough 78.3% of all the participants had been exposed to SHS (78.1%subjects vs 78.5% controls), there were no statistical significance of cervicalcytological abnormalities and SHS exposure status (never, former, currentexposure), exposure intensity in cigarettes per day (none, 1–9, 10–19, and≥20), SHS exposure duration in years (none, 1–9, 10–19, and ≥20) and theBrinkman Index (BI) (none, 1–99, 100–399, ≥400) between the two groups. Theunivariate analysis results showed that there were statistical differences betweensubjects and controls in marital status, sexual frequency in past year, numberof sexual partners, age at first intercourse, age at first delivery. The stratifiedCox regression model only showed that the age at first sexual intercourse wasassociated with the cervical cytological abnormalities (OR=1.206, 95% CI: 1.104–1.319).ConclusionsStudies on the association between SHS exposure and cervical lesionshave been equivocal. In this study, the SHS exposure could not be detected asan independent risk factor of abnormal cervical cytology among Chinese adultwomen.
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