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Crystal Structures of Two Bacterial 3-Hydroxy-3-methylglutaryl-CoA Lyases Suggest a Common Catalytic Mechanism among a Family of TIM Barrel Metalloenzymes Cleaving Carbon-Carbon Bonds

机译：两种细菌3-羟基-3-甲基丁酸咖啡酶的晶体结构表明了一系列碳碳键的Tim桶金属酶系列中常见的催化机制

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Farhad Forouhar; Munif Hussain; Ramy Farid; Jordi Benach; Mariam Abashidze; William C. Edstrom; Sergey M. Vorobiev; Rong Xiao; Thomas B. Acton; Zhuji Fu; Jung-Ja P. Kim; Henry M. Miziorko; Gaetano T. Montelione; John F. Hunt;
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1. Alginate Lyase Aly36B is a New Bacterial Member of the Polysaccharide Lyase Family 36 and Catalyzes by a Novel Mechanism With Lysine as Both the Catalytic Base and Catalytic Acid [J] . Dong Fang, Xu Fei, Chen Xiu-Lan, Journal of Molecular Biology . 2019,第24期

机译：藻酸盐裂解酶Aly36b是多糖裂解酶系列36的新细菌构件36，并通过与赖氨酸的新机制催化为催化基质和催化酸
2. Novel Molecular Insights into the Catalytic Mechanism of Marine Bacterial Alginate Lyase AlyGC from Polysaccharide Lyase Family 6 [J] . Fei Xu, Fang Dong, Peng Wang, The Journal of biological chemistry . 2017,第11期

机译：多糖裂解酶家族6的海洋细菌藻酸盐裂解酶AlyGC催化机理的新型分子洞察。
3. Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for the FAH family [J] . Dongqing Xu, Langlai Xu, May Marsh, The biochemical journal . 2013,第1期

机译：Cg1458的晶体结构揭示了FAH家族的催化盖结构域和常见的催化机理
4. Understanding the mechanisms of carbon-carbon and carbon-nitrogen bond forming processes in catalytic reactions. [D] . Shekhar, Shashank. 2006

机译：了解催化反应中碳-碳和碳-氮键形成过程的机理。
5. Insights into TIM-barrel Prenyl Transferase Mechanisms: Crystal Structures of PcrB from Bacillus subtilis and Staphylococcus aureus [O] . Feifei Ren, Xinxin Feng, Dr. Tzu-Ping Ko, -1

机译：探讨Tim-Barrel戊烯转移酶机制：来自枯草芽孢杆菌和金黄色葡萄球菌的PCRB晶体结构
6. Structure and mechanism of bacterial dehalogenases: different ways to cleave a carbon-halogen bond:different ways to cleave a carbon–halogen bond [O] . de Jong R.M., Dijkstra B.W. 2003

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Crystal Structures of Two Bacterial 3-Hydroxy-3-methylglutaryl-CoA Lyases Suggest a Common Catalytic Mechanism among a Family of TIM Barrel Metalloenzymes Cleaving Carbon-Carbon Bonds

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