首页> 外文OA文献 >Tyrosine Kinase Inhibitors. 19. 6-Alkynamides of 4-Anilinoquinazolines and 4-Anilinopyrido3, 4-dpyrimidines as Irreversible Inhibitors of the erbB Family of Tyrosine Kinase Receptors

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Tyrosine Kinase Inhibitors. 19. 6-Alkynamides of 4-Anilinoquinazolines and 4-Anilinopyrido3, 4-dpyrimidines as Irreversible Inhibitors of the erbB Family of Tyrosine Kinase Receptors

机译：酪氨酸激酶抑制剂。 19. 4-苯胺喹唑啉和4-苯胺吡啶喹啉3,4-D嘧啶的6-醇胺作为酪氨酸激酶受体的Irbb B家族的不可逆抑制剂

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1. Tyrosine kinase inhibitors. 19. 6-alkynamides of 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as irreversible inhibitors of the erbB family of tyrosine kinase receptors [J] . Klutchko SR, Zhou HR, Winters RT, Journal of Medicinal Chemistry . 2006,第4期

机译：酪氨酸激酶抑制剂。 19. 4-苯胺基喹唑啉和4-苯胺基吡啶并[3,4-d]嘧啶的6-炔酰胺作为酪氨酸激酶受体的erbB家族的不可逆抑制剂
2. Tyrosine kinase inhibitors. 18. 6-Substituted 4-anilinoquinazolines and 4-anilinopyrido(3,4-d)pyrimidines as soluble, irreversible inhibitors of the epidermal growth factor receptor. [J] . Smaill JB, Showalter HD, Zhou H, Journal of Medicinal Chemistry . 2001,第3期

机译：酪氨酸激酶抑制剂。 18. 6-取代的4-苯胺基喹唑啉和4-苯胺基吡啶并（3,4-d）嘧啶为表皮生长因子受体的可溶性，不可逆抑制剂。
3. Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family [J] . Smaill Jeff B., Gonzales Andrea J., Spicer Julie A., Journal of Medicinal Chemistry . 2016,第17期

机译：酪氨酸激酶抑制剂。 20.取代的喹唑啉和吡啶并[3,4-d]嘧啶衍生物作为表皮生长因子受体家族的口服活性，不可逆抑制剂的优化
4. Pyrrolo2,3-dpyrimidine and Pyrazolo3,4-dpyrimidine Derivatives as Selective Inhibitors of the EGF Receptor Tyrosine Kinase [C] . G. Caravatti, J. Bruggen, E. Buchdunger, American Chemical Society . 2001

机译：Pyrrolo 2,3-D嘧啶和吡唑3,4-D嘧啶衍生物作为EGF受体酪氨酸激酶的选择性抑制剂
5. The multi-targeted receptor tyrosine kinase inhibitor, linifanib (ABT-869), induces apoptosis and inhibits proliferation of leukemia cells through phosphoinositide-3 kinase (PI3K)/AKT-dependent signaling pathways. [D] . Hernandez, Jenny Elizabeth. 2010

机译：多靶点受体酪氨酸激酶抑制剂利尼法尼（ABT-869）通过磷酸肌醇3激酶（PI3K）/ AKT依赖性信号传导途径诱导凋亡并抑制白血病细胞的增殖。
6. Efficacy of the Irreversible ErbB Family Blocker Afatinib in Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI)–Pretreated Non–Small-Cell Lung Cancer Patients with Brain Metastases or Leptomeningeal Disease [O] . Petra Hoffknecht, Amanda Tufman, Thomas Wehler, -1

机译：不可逆的ErbB家族阻滞剂Afatinib在表皮生长因子受体（EGFR）酪氨酸激酶抑制剂（TKI）预处理的非小细胞肺癌脑转移或软脑膜病患者中的疗效
7. Efficacy of the Irreversible ErbB Family Blocker Afatinib in Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI)–Pretreated Non–Small-Cell Lung Cancer Patients with Brain Metastases or Leptomeningeal Disease [O] . Hoffknecht Petra, Tufman Amanda, Wehler Thomas, 2015

机译：不可逆的ErbB家族阻滞剂Afatinib在表皮生长因子受体（EGFR）酪氨酸激酶抑制剂（TKI）预处理的非小细胞肺癌伴脑转移或软脑膜病患者中的疗效
8. Isolation and Analysis of Human Kekkon-Like Molecules, a Family of Potential Inhibitors of ErbB Receptor Tyrosine Kinases [R] . Kockel, L. 2005

机译：人类Kekkon样分子的分离和分析，一系列ErbB受体酪氨酸激酶的潜在抑制剂

Tyrosine Kinase Inhibitors. 19. 6-Alkynamides of 4-Anilinoquinazolines and 4-Anilinopyrido3, 4-dpyrimidines as Irreversible Inhibitors of the erbB Family of Tyrosine Kinase Receptors

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