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MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice

机译：基于Multitep平台的DNA表位疫苗靶向Tau的N-末端诱导强烈的免疫反应，减少Thy-Tau22小鼠的Tau病理学

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Hayk Davtyan; Wesley W. Chen; Karen Zagorski; Joy Davis; Irina Petrushina; Konstantin Kazarian; David H. Cribbs; Michael G. Agadjanyan; Mathew Blurton-Jones; Anahit Ghochikyan;
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1. 猪endoglin胞外段DNA疫苗诱导抗小鼠结肠癌免疫反应 [J] . 焦解歌, 张阳德, 黎岳南癌症（英文版） . 2005,第010期
2. A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice [J] . Armine Hovakimyan, Tatevik Antonyan, Sepideh Kiani Shabestari, Scientific reports. . 2019,第1期

机译：靶向TAU的磷酸酶活性结构域（垫）的基于多人平台的表位疫苗：PS19小鼠中的治疗效果
3. Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice [J] . Hayk Davtyan, Armine Hovakimyan, Sepideh Kiani Shabestari, Alzheimer s Research & Therapy . 2019,第1期

机译：测试基于Multitep的组合疫苗以减少Tau22 / 5xFAD面部大鼠的Aβ和Tau病理
4. Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology [J] . Neurobiology of disease . 2020,第期

机译：用Tauopathy诱导强抗体反应的小鼠模型与Tau表位的主动免疫与短记忆和普斯卡396-tau病理学的改善
5. Humoral Immune Response Induced in Outbred CD1 Mice by DNA Vaccine Against African Trypanosomiasis [C] . M. Sousa Silva, G.A. Monteiro, J. Atouguia, International Congress of Parasitology . 2006

机译：DNA疫苗对非洲锥虫病患者的近期CD1小鼠诱导的体液免疫应答
6. L-BLP25 Vaccine plus Letrozole Induces a TH1 Immune Response and has Additive Antitumor Activity in MUC-1 Expressing Mammary Tumors in Mice. [D] . Mehta, Neelima Rakesh. 2012

机译：L-BLP25疫苗加来曲唑在小鼠中表达MUC-1的乳腺肿瘤中诱导TH1免疫反应并具有累加的抗肿瘤活性。
7. MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice [O] . Hayk Davtyan, Wesley W. Chen, Karen Zagorsky, -1

机译：靶向tau N端的基于MultiTEP平台的DNA表位疫苗诱导THY-Tau22小鼠强烈的免疫反应并降低tau病理
8. Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice [O] . Hayk Davtyan, Armine Hovakimyan, Sepideh Kiani Shabestari, 2019

机译：测试基于Multitep的组合疫苗以减少Tau22 / 5xFAD面部大鼠的Aβ和Tau病理

MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice

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