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Target guided synthesis of 5-benzyl-2, 4, -diamonopyrimidines: Their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from plasmodium falciparum

机译：目标引导合成5-苄基-2,4， - 丁络嘧啶：它们对野生型和突变二氢醇的抗疟疾活性和结合亲和力来自疟原虫的野生型和突变二氢脱液还原酶

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1. Target Guided Synthesis of 5-Benzyl-2,4-diamonopyrimidines: Their Antimalarial Activities and Binding Affinities to Wild Type and Mutant Dihydrofolate Reductases from Plasmodium falciparum [J] . Chawanee Sirichaiwat, Chakapong Intaraudom, Sumalee Kamchonwongpaisan, Journal of Medicinal Chemistry . 2004,第2期

机译：目标指导的5-苄基-2,4-diamonopyrimidines的合成：它们的抗疟活性和对恶性疟原虫野生型和突变型二氢叶酸还原酶的结合亲和力。
2. Homology modeling of wild type and pyrimethamine/cycloguanil-cross resistant mutant type Plasmodium falciparum dihydrofolate reductase. A model for antimalarial chemotherapy resistance. [J] . Santos-Filho OA, de-Alencastro RB, Figueroa-Villar JD Biophysical Chemistry: An International Journal Devoted to the Physical Chemistry of Biological Phenomena . 2001,第3期

机译：野生型和乙胺嘧啶/环鸟嘌呤交叉抗性突变型恶性疟原虫二氢叶酸还原酶的同源性建模。抗疟疾化疗耐药性模型。
3. Stoichiometric selection of tight-binding inhibitors by wild-type and mutant forms of malarial (Plasmodium falciparum) dihydrofolate reductase [J] . Kamchonwongpaisan S, Vanichtanankul J, Tarnchompoo B, Analytical chemistry . 2005,第5期

机译：野生型和突变形式的疟疾（恶性疟原虫）二氢叶酸还原酶的化学结合选择紧密结合抑制剂
4. Crystal Structures of Wild-type and Mutants of Pea Ferredoxin: NADP~+ Reductase: A Productive NADP~+ Binding Mode and Its Mechanistic Significance [C] . Deng Z., Arkaki A.K., Carrillo N., International symposium on mechanisms of enzymatic catalysis . 1998

机译：豌豆铁氧还蛋白野生型及其突变体的晶体结构：NADP〜+还原酶：一种有效的NADP〜+结合方式及其机理学意义
5. Characterization of folate cycle enzymes in Plasmodium falciparum: Ligand binding properties of dihydrofolate reductase, thymidylate synthase, and serine hydroxymethyltransferase. [D] . Pang, Cullen Kwai Tim. 2008

机译：恶性疟原虫中叶酸循环酶的特征：二氢叶酸还原酶，胸苷酸合酶和丝氨酸羟甲基转移酶的配体结合特性。
6. Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains [O] . Tuo Yang, Stanley C. Xie, Pengxing Cao, 2016

机译：合成的臭氧活性抗疟药和双氢青蒿素对K13野生型和突变性恶性疟原虫菌株活性的暴露时间依赖性的比较
7. Inhibitors of multiple mutants of Plasmodium falciparum dihydrofolate reductase and their antimalarial activities [O] . Sumalee Kamchonwongpaisan, Rachel Quarrell, Netnapa Charoensetakul, 2004

机译：恶性疟原虫二氢叶酸还原酶多种突变体的抑制剂及其抗疟活性

Target guided synthesis of 5-benzyl-2, 4, -diamonopyrimidines: Their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from plasmodium falciparum

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